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Gon4l Gene Detail
Summary
  • Symbol
    Gon4l
  • Name
    gon-4 like
  • Synonyms
    1500041I23Rik, 2610100B20Rik, mKIAA1606
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917579
    NCBI Gene: 76022
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr3:88742531-88817406 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 39.00 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1634 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917579
 protein coding gene Chr3:88742531-88817410 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027409
 protein coding gene Chr3:88981445-89076095 (+)
A/J MGP_AJ_G0027373
 protein coding gene Chr3:86009865-86146638 (+)
AKR/J MGP_AKRJ_G0027337
 protein coding gene Chr3:88074148-88229022 (+)
BALB/cJ MGP_BALBcJ_G0027382
 protein coding gene Chr3:86037691-86114585 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0027828
 protein coding gene Chr3:92268842-92436713 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025180
 protein coding gene Chr3:81559489-81602858 (+)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0027098
 protein coding gene Chr3:95495369-95629461 (+)
DBA/2J MGP_DBA2J_G0027236
 protein coding gene Chr3:85445867-85524293 (+)
FVB/NJ MGP_FVBNJ_G0027204
 protein coding gene Chr3:83698994-83862008 (+)
LP/J MGP_LPJ_G0027345
 protein coding gene Chr3:89975539-90179403 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0027887
 protein coding gene Chr3:87820287-87976355 (+)
PWK/PhJ MGP_PWKPhJ_G0026304
 protein coding gene Chr3:85225676-85394507 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026123
 protein coding gene Chr3:87007402-87137655 (+)
WSB/EiJ MGP_WSBEiJ_G0026652
 protein coding gene Chr3:88248701-88363267 (+)



Homology
more
  • Human Ortholog
    GON4L, gon-4 like
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GON4L, gon-4 like
  • Synonyms
    GON-4, GON4, YARP
  • Links
    NCBI Gene ID: 54856
    neXtProt AC: NX_Q3T8J9
    UniProt: Q3T8J9

  • Chr Location
    1q22; chr1:155745112-155859431 (-)  GRCh38
  • Human Ortholog
    YY1AP1, YY1 associated protein 1
  • Synonyms
    GRNG, HCCA1, HCCA2, YY1AP
  • Links
    NCBI Gene ID: 55249
    neXtProt AC: NX_Q9H869
    UniProt: Q9H869

  • Chr Location
    1q22; chr1:155659442-155689334 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Gon4l mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced allele exhibit arrested B cell development at the early pro-B cell stage.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 76022 NCBI Gene Model | MGI Sequence Detail 74876 C57BL/6J ±  kb
    transcript NM_001242372 RefSeq | MGI Sequence Detail 7587 C57BL/6  
    polypeptide Q9DB00 UniProt | EBI | MGI Sequence Detail 2260 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 11

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1916251
    References
    more
    • Summaries
      All 40
      Diseases 2
      Gene Ontology 4
      Phenotypes 14
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:341845 Colgan DF, et al., The transcriptional regulator GON4L is required for viability and hematopoiesis in mice. Exp Hematol. 2021 Jun;98:25-35
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory