Polr1g MGI Mouse Gene Detail - MGI:1917583 - RNA polymerase I subunit G

Symbol

Polr1g
Name

RNA polymerase I subunit G
Synonyms

2610103M17Rik, Ase1, Cd3eap, PAF49

Feature Type

protein coding gene
IDs

MGI:1917583
NCBI Gene: 70333
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr7:19089939-19093408 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 9.62 cM
Mapping Data

1 experiment

SNPs within 2kb

166 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1917583	protein coding gene	Chr7:19089932-19093408 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0031772	protein coding gene	Chr7:17353584-17356187 (-)
A/J	MGP_AJ_G0031748	protein coding gene	Chr7:17000664-17003301 (-)
AKR/J	MGP_AKRJ_G0031674	protein coding gene	Chr7:17471437-17474094 (-)
BALB/cJ	MGP_BALBcJ_G0031753	protein coding gene	Chr7:17203327-17206442 (-)
C3H/HeJ	MGP_C3HHeJ_G0031475	protein coding gene	Chr7:17732436-17735062 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0032219	protein coding gene	Chr7:18229722-18232356 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0029285	protein coding gene	Chr7:18647287-18649868 (-)
CAST/EiJ	MGP_CASTEiJ_G0030818	protein coding gene	Chr7:14143160-14147116 (-)
CBA/J	MGP_CBAJ_G0031437	protein coding gene	Chr7:18889926-18892545 (-)
DBA/2J	MGP_DBA2J_G0031592	protein coding gene	Chr7:16944314-16946942 (-)
FVB/NJ	MGP_FVBNJ_G0031544	protein coding gene	Chr7:16807637-16808281 (-)
LP/J	MGP_LPJ_G0031675	protein coding gene	Chr7:17674301-17681044 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0031580	protein coding gene	Chr7:18744307-18746937 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0032247	protein coding gene	Chr7:17072855-17075498 (-)
PWK/PhJ	MGP_PWKPhJ_G0030542	protein coding gene	Chr7:14036416-14039205 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0030369	protein coding gene	Chr7:11784370-11786996 (-)
WSB/EiJ	MGP_WSBEiJ_G0030918	protein coding gene	Chr7:17296169-17298802 (-)

Human Ortholog

POLR1G, RNA polymerase I subunit G

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

POLR1G, RNA polymerase I subunit G
Synonyms

ASE-1, ASE1, CAST, CD3EAP, PAF49, RPA34
Links

HGNC:24219

NCBI Gene ID: 10849

neXtProt AC: NX_O15446

UniProt: O15446
Chr Location

19q13.32; chr19:45406644-45410737 (+) GRCh38

MGI Vertebrate Homology

Polr1g stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: POLR1G
Gene Tree

Polr1g

Diseases

1 with human POLR1G associations

				Human Disease	Mouse Models
				multiple myeloma IDs multiple myeloma DOID:9538 EFO:0001378 ICD10CM:C90.0 ICD9CM:203.0 MESH:D009101 NCI:C3242 OMIM:254500 ORDO:29073 UMLS_CUI:C0026764

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
7 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

5
Gene trapped

2
Targeted

3
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

11 strains or lines available

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All GO Annotations

14
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

739
Tissues

23
cDNA Data

35
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

34
RefSeq

2
UniProt

2
CCDS

CCDS39798.1

Ensembl

ENSMUSG00000047649 (Evidence)
NCBI Gene

70333

			Length	Strain/Species	Flank
genomic	ENSMUSG00000047649	Ensembl Gene Model \| MGI Sequence Detail	3470	C57BL/6J	± kb
transcript	ENSMUST00000047036	Ensembl \| MGI Sequence Detail	2239	Not Applicable
polypeptide	ENSMUSP00000044653	Ensembl \| MGI Sequence Detail	399	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000005171 DNA-directed RNA polymerase I subunit RPA34

(term hierarchy)
InterPro Domains

IPR013240 DNA-directed RNA polymerase I, subunit RPA34

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All nucleic 35

cDNA 35

Microarray probesets 2

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MGI:7382828

Summaries

All 32

Developmental Gene Expression 2

Gene Ontology 4

Phenotypes 7
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Polr1g:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr70911	Chr7:19093402-19093413 (-)	0 bp
Tssr70910	Chr7:19093341-19093401 (-)	37 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24