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St13 Gene Detail
Summary
  • Symbol
    St13
  • Name
    suppression of tumorigenicity 13
  • Synonyms
    1110007I03Rik, 3110002K08Rik, Hsp70 interacting protein, HSPABP1, p48, PRO0786, SNC6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917606
    NCBI Gene: 70356
  • Alliance
    gene page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:81247870-81284278 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 38.07 cM, cytoband E2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    741 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917606
 protein coding gene Chr15:81247869-81284278 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022110
 protein coding gene Chr15:81785597-81821945 (-)
A/J MGP_AJ_G0022071
 protein coding gene Chr15:78911422-78948006 (-)
AKR/J MGP_AKRJ_G0022046
 protein coding gene Chr15:81107764-81144231 (-)
BALB/cJ MGP_BALBcJ_G0022077
 protein coding gene Chr15:78940441-78976798 (-)
C3H/HeJ MGP_C3HHeJ_G0021848
 protein coding gene Chr15:81101558-81138550 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022520
 protein coding gene Chr15:84978474-85016271 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020050
 protein coding gene Chr15:75379644-75418794 (-)
CAST/EiJ MGP_CASTEiJ_G0021369
 protein coding gene Chr15:81856133-81895531 (-)
CBA/J MGP_CBAJ_G0021813
 protein coding gene Chr15:87634866-87671173 (-)
DBA/2J MGP_DBA2J_G0021942
 protein coding gene Chr15:78394163-78430633 (-)
FVB/NJ MGP_FVBNJ_G0021920
 protein coding gene Chr15:77434021-77470953 (-)
LP/J MGP_LPJ_G0022010
 protein coding gene Chr15:81943878-81980438 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021940
 protein coding gene Chr15:92611478-92648871 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022534
 protein coding gene Chr15:81169705-81208887 (-)
PWK/PhJ MGP_PWKPhJ_G0021111
 protein coding gene Chr15:78421633-78458847 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020948
 protein coding gene Chr15:80968831-81004712 (-)
WSB/EiJ MGP_WSBEiJ_G0021421
 protein coding gene Chr15:81597458-81635007 (-)



Homology
more
  • Human Ortholog
    ST13, ST13 Hsp70 interacting protein
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ST13, ST13 Hsp70 interacting protein
  • Synonyms
    AAG2, FAM10A1, FAM10A4, HIP, HOP, HSPABP, HSPABP1, P48, PRO0786, SNC6
  • Links
    NCBI Gene ID: 6767
    neXtProt AC: NX_P50502
    UniProt: P50502

  • Chr Location
    22q13.2; chr22:40824535-40856639 (-)  GRCh38
  • Human Ortholog
    ST13P4, ST13, Hsp70 interacting protein pseudogene 4
  • Synonyms
    FAM10A4, FAM10A4P
  • Links
    NCBI Gene ID: 145165
    UniProt: Q8IZP2

  • Chr Location
    13q14.2; chr13:50172018-50173616 (+)  GRCh38
  • Human Ortholog
    ST13P5, ST13, Hsp70 interacting protein pseudogene 5
  • Synonyms
    FAM10A5
  • Links
    NCBI Gene ID: 144106
    UniProt: Q8NFI4

  • Chr Location
    11p15.1; chr11:18261885-18263501 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    32 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    236
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022403 Ensembl Gene Model | MGI Sequence Detail 36409 C57BL/6J ±  kb
transcript ENSMUST00000172107 Ensembl | MGI Sequence Detail 3346 Not Applicable  
polypeptide ENSMUSP00000130195 Ensembl | MGI Sequence Detail 371 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 236
    cDNA 236

    Microarray probesets 5
Other
Accession IDs
less
MGI:1915742, MGI:2146239
References
more
  • Summaries
    All 61
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 6
    Phenotypes 32
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory