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Tecpr1 Gene Detail
Summary
  • Symbol
    Tecpr1
  • Name
    tectonin beta-propeller repeat containing 1
  • Synonyms
    2210010N04Rik, mKIAA1358
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917631
    NCBI Gene: 70381
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:144131260-144160433 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 83.07 cM, cytoband G2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    977 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917631
 protein coding gene Chr5:144131260-144160433 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030347
 protein coding gene Chr5:149518221-149550025 (-)
A/J MGP_AJ_G0030316
 protein coding gene Chr5:143103716-143132596 (-)
AKR/J MGP_AKRJ_G0030248
 protein coding gene Chr5:147558789-147591885 (-)
BALB/cJ MGP_BALBcJ_G0030333
 protein coding gene Chr5:144348899-144384271 (-)
C3H/HeJ MGP_C3HHeJ_G0030044
 protein coding gene Chr5:148402057-148431162 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030778
 protein coding gene Chr5:154992391-155022859 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027997
 protein coding gene Chr5:136892043-136921602 (-)
CAST/EiJ MGP_CASTEiJ_G0029449
 protein coding gene Chr5:147923069-147952900 (-)
CBA/J MGP_CBAJ_G0030014
 protein coding gene Chr5:161351253-161379967 (-)
DBA/2J MGP_DBA2J_G0030164
 protein coding gene Chr5:142853944-142882899 (-)
FVB/NJ MGP_FVBNJ_G0030119
 protein coding gene Chr5:142072655-142102436 (-)
LP/J MGP_LPJ_G0030250
 protein coding gene Chr5:150131531-150160595 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030150
 protein coding gene Chr5:163722515-163754939 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030818
 protein coding gene Chr5:147447611-147478118 (-)
PWK/PhJ MGP_PWKPhJ_G0029164
 protein coding gene Chr5:141964582-141993665 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029000
 protein coding gene Chr5:145184770-145219405 (-)
WSB/EiJ MGP_WSBEiJ_G0029522
 protein coding gene Chr5:148255578-148285647 (-)



Homology
more
  • Human Ortholog
    TECPR1, tectonin beta-propeller repeat containing 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TECPR1, tectonin beta-propeller repeat containing 1
  • Links
    NCBI Gene ID: 25851
    neXtProt AC: NX_Q7Z6L1
    UniProt: Q7Z6L1

  • Chr Location
    7q21.3; chr7:98214624-98252232 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit impaired selective autophagy and abnormal response to bacterial infection in MEFs.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    735
  • Tissues
    29
  • cDNA Data
    8
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70381 NCBI Gene Model | MGI Sequence Detail 29174 C57BL/6J ±  kb
transcript NM_001356992 RefSeq | MGI Sequence Detail 5544 C57BL/6  
polypeptide Q80VP0 UniProt | EBI | MGI Sequence Detail 1166 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000030660 tectonin beta-propeller repeat-containing protein 1
    (term hierarchy)
  • InterPro Domains
    IPR006624 Beta-propeller repeat TECPR
    IPR010482 Peroxin domain
    IPR006614 Peroxin/Ferlin domain
    IPR011993 PH-like domain superfamily
    IPR051513 Tectonin beta-propeller repeat-containing
  • GlyGen
    Q80VP0 6 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (4 sites)
Molecular
Reagents
less
  • All nucleic 10
    cDNA 9
    Other 1

    Microarray probesets 5
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory