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Kctd2 Gene Detail
Summary
  • Symbol
    Kctd2
  • Name
    potassium channel tetramerisation domain containing 2
  • Synonyms
    2310012I15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917632
    NCBI Gene: 70382
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:115310954-115322100 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 80.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    387 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917632
 protein coding gene Chr11:115310915-115322100 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019386
 protein coding gene Chr11:119441492-119454769 (+)
A/J MGP_AJ_G0019355
 protein coding gene Chr11:114227163-114238639 (+)
AKR/J MGP_AKRJ_G0019325
 protein coding gene Chr11:117634556-117645773 (+)
BALB/cJ MGP_BALBcJ_G0019329
 protein coding gene Chr11:114640717-114651911 (+)
C3H/HeJ MGP_C3HHeJ_G0019135
 protein coding gene Chr11:117985533-117998798 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019779
 protein coding gene Chr11:123083702-123094848 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017402
 protein coding gene Chr11:111266389-111277781 (+)
CAST/EiJ MGP_CASTEiJ_G0018690
 protein coding gene Chr11:119298184-119310861 (+)
CBA/J MGP_CBAJ_G0019107
 protein coding gene Chr11:127936895-127950160 (+)
DBA/2J MGP_DBA2J_G0019218
 protein coding gene Chr11:113663062-113674239 (+)
FVB/NJ MGP_FVBNJ_G0019210
 protein coding gene Chr11:113138628-113149812 (+)
LP/J MGP_LPJ_G0019288
 protein coding gene Chr11:119827466-119839234 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019243
 protein coding gene Chr11:127112442-127125718 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019817
 protein coding gene Chr11:118290275-118301756 (+)
PWK/PhJ MGP_PWKPhJ_G0018454
 protein coding gene Chr11:114945688-114956899 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018247
 protein coding gene Chr11:118036608-118047568 (+)
WSB/EiJ MGP_WSBEiJ_G0018742
 protein coding gene Chr11:118239291-118250491 (+)



Homology
more
  • Human Ortholog
    KCTD2, potassium channel tetramerization domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KCTD2, potassium channel tetramerization domain containing 2
  • Links
    NCBI Gene ID: 23510
    neXtProt AC: NX_Q14681
    UniProt: Q14681

  • Chr Location
    17q25.1; chr17:75032571-75065889 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    49
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000016940 Ensembl Gene Model | MGI Sequence Detail 11147 C57BL/6J ±  kb
transcript ENSMUST00000106533 Ensembl | MGI Sequence Detail 2649 Not Applicable  
polypeptide ENSMUSP00000102143 Ensembl | MGI Sequence Detail 338 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 50
    cDNA 50

    Microarray probesets 4
References
more
  • Summaries
    All 27
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory