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Cenpl Gene Detail
Summary
  • Symbol
    Cenpl
  • Name
    centromere protein L
  • Synonyms
    2610300B10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917704
    NCBI Gene: 70454
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:160898337-160914294 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 69.75 cM, cytoband H1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    500 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917704
 protein coding gene Chr1:160898283-160914294 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016648
 protein coding gene Chr1:166325345-166341182 (+)
A/J MGP_AJ_G0016629
 protein coding gene Chr1:159555592-159571582 (+)
AKR/J MGP_AKRJ_G0016595
 protein coding gene Chr1:164423605-164439552 (+)
BALB/cJ MGP_BALBcJ_G0016590
 protein coding gene Chr1:160096193-160112016 (+)
C3H/HeJ MGP_C3HHeJ_G0016414
 protein coding gene Chr1:164623112-164641222 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017051
 protein coding gene Chr1:171971240-171990154 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014760
 protein coding gene Chr1:151673479-151691511 (+)
CAST/EiJ MGP_CASTEiJ_G0015994
 protein coding gene Chr1:164237203-164253879 (+)
CBA/J MGP_CBAJ_G0016389
 protein coding gene Chr1:178060563-178079265 (+)
DBA/2J MGP_DBA2J_G0016495
 protein coding gene Chr1:158533578-158549383 (+)
FVB/NJ MGP_FVBNJ_G0016493
 protein coding gene Chr1:156943669-156959581 (+)
LP/J MGP_LPJ_G0016566
 protein coding gene Chr1:167412525-167431900 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016518
 protein coding gene Chr1:185623565-185640361 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017087
 protein coding gene Chr1:164241117-164257933 (+)
PWK/PhJ MGP_PWKPhJ_G0015780
 protein coding gene Chr1:157690132-157706821 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015567
 protein coding gene Chr1:163140570-163162160 (+)
WSB/EiJ MGP_WSBEiJ_G0016056
 protein coding gene Chr1:164433022-164448801 (+)



Homology
more
  • Human Ortholog
    CENPL, centromere protein L
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CENPL, centromere protein L
  • Synonyms
    C1orf155, CENP-L, dJ383J4.3
  • Links
    NCBI Gene ID: 91687
    neXtProt AC: NX_Q8N0S6
    UniProt: Q8N0S6

  • Chr Location
    1q25.1; chr1:173799550-173824883 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • cDNA Data
    54
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 70454 NCBI Gene Model | MGI Sequence Detail 15958 C57BL/6J ±  kb
transcript NR_131028 RefSeq | MGI Sequence Detail 2470 C57BL/6  
polypeptide Q3U3S3 UniProt | EBI | MGI Sequence Detail 329 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 55
    cDNA 55

    Microarray probesets 3
Other
Accession IDs
less
MGI:2138564, MGI:2138609
References
more
  • Summaries
    All 41
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory