About   Help   FAQ
Snx21 Gene Detail
Summary
  • Symbol
    Snx21
  • Name
    sorting nexin family member 21
  • Synonyms
    5730407K14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917729
    NCBI Gene: 101113
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164627743-164635736 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 85.27 cM, cytoband H3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    256 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917729
 protein coding gene Chr2:164627535-164635736 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026873
 protein coding gene Chr2:170286954-170294917 (+)
A/J MGP_AJ_G0026840
 protein coding gene Chr2:163324376-163332373 (+)
AKR/J MGP_AKRJ_G0026811
 protein coding gene Chr2:168178602-168186623 (+)
BALB/cJ MGP_BALBcJ_G0026849
 protein coding gene Chr2:163683858-163691854 (+)
C3H/HeJ MGP_C3HHeJ_G0026591
 protein coding gene Chr2:168542344-168550308 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027296
 protein coding gene Chr2:175215736-175223714 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024667
 protein coding gene Chr2:156730389-156738495 (+)
CAST/EiJ MGP_CASTEiJ_G0026049
 protein coding gene Chr2:168959759-168967717 (+)
CBA/J MGP_CBAJ_G0026568
 protein coding gene Chr2:181573567-181581524 (+)
DBA/2J MGP_DBA2J_G0026706
 protein coding gene Chr2:162490094-162498060 (+)
FVB/NJ MGP_FVBNJ_G0026672
 protein coding gene Chr2:160910496-160918456 (+)
LP/J MGP_LPJ_G0026808
 protein coding gene Chr2:170346380-170354336 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026691
 protein coding gene Chr2:185142299-185150283 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027353
 protein coding gene Chr2:168085699-168093666 (+)
PWK/PhJ MGP_PWKPhJ_G0025786
 protein coding gene Chr2:162090676-162098728 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025587
 protein coding gene Chr2:166981808-166989842 (+)
WSB/EiJ MGP_WSBEiJ_G0026122
 protein coding gene Chr2:168966725-168974715 (+)



Homology
more
  • Human Ortholog
    SNX21, sorting nexin family member 21
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SNX21, sorting nexin family member 21
  • Synonyms
    C20orf161, dJ337O18.4, PP3993, SNX-L, SNXL
  • Links
    NCBI Gene ID: 90203
    neXtProt AC: NX_Q969T3
    UniProt: Q969T3

  • Chr Location
    20q13.12; chr20:45833799-45843276 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    6
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050373 Ensembl Gene Model | MGI Sequence Detail 7994 C57BL/6J ±  kb
transcript ENSMUST00000056181 Ensembl | MGI Sequence Detail 2590 Not Applicable  
polypeptide ENSMUSP00000054137 Ensembl | MGI Sequence Detail 363 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141431
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory