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Cpsf7 Gene Detail
Summary
  • Symbol
    Cpsf7
  • Name
    cleavage and polyadenylation specific factor 7
  • Synonyms
    5730453I16Rik, C330017N18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917826
    NCBI Gene: 269061
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:10502630-10525017 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 6.60 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    465 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917826
 protein coding gene Chr19:10502594-10525099 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024847
 protein coding gene Chr19:7870522-7894362 (+)
A/J MGP_AJ_G0024815
 protein coding gene Chr19:7333320-7356974 (+)
AKR/J MGP_AKRJ_G0024790
 protein coding gene Chr19:7623171-7646957 (+)
BALB/cJ MGP_BALBcJ_G0024815
 protein coding gene Chr19:7378282-7401348 (+)
C3H/HeJ MGP_C3HHeJ_G0024581
 protein coding gene Chr19:7509973-7531999 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025263
 protein coding gene Chr19:8228791-8253471 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022690
 protein coding gene Chr19:7753365-7776865 (+)
CAST/EiJ MGP_CASTEiJ_G0024054
 protein coding gene Chr19:7163767-7185554 (+)
CBA/J MGP_CBAJ_G0024555
 protein coding gene Chr19:8271938-8296774 (+)
DBA/2J MGP_DBA2J_G0024682
 protein coding gene Chr19:7345771-7368863 (+)
FVB/NJ MGP_FVBNJ_G0024649
 protein coding gene Chr19:7389486-7410338 (+)
LP/J MGP_LPJ_G0024769
 protein coding gene Chr19:7834937-7859424 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024676
 protein coding gene Chr19:8164541-8201395 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025311
 protein coding gene Chr19:7641441-7667478 (+)
PWK/PhJ MGP_PWKPhJ_G0023799
 protein coding gene Chr19:6788288-6811484 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023604
 protein coding gene Chr19:6822816-6845208 (+)
WSB/EiJ MGP_WSBEiJ_G0024116
 protein coding gene Chr19:7525446-7548587 (+)



Homology
more
  • Human Ortholog
    CPSF7, cleavage and polyadenylation specific factor 7
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CPSF7, cleavage and polyadenylation specific factor 7
  • Synonyms
    CFIm59
  • Links
    NCBI Gene ID: 79869
    neXtProt AC: NX_Q8N684
    UniProt: Q8N684

  • Chr Location
    11q12.2; chr11:61402641-61430031 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    756
  • Tissues
    42
  • cDNA Data
    12
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034820 Ensembl Gene Model | MGI Sequence Detail 22388 C57BL/6J ±  kb
    transcript ENSMUST00000237321 Ensembl | MGI Sequence Detail 1760 Not Applicable  
    polypeptide ENSMUSP00000157834 Ensembl | MGI Sequence Detail 471 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      5 Sequences
    • Protein Ontology
      PR:000005834 cleavage and polyadenylation specificity factor subunit 7
      (term hierarchy)
    • InterPro Domains
      IPR034772 CPSF6/7 family
      IPR034773 CPSF7, RNA recognition motif
      IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
      IPR035979 RNA-binding domain superfamily
      IPR000504 RNA recognition motif domain
    • GlyGen
      Q8BTV2 2 sites, 2 N-linked glycans (2 sites)
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 16
      Primer pair 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1924447, MGI:2147625
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 5
      Gene Ontology 5
      Phenotypes 7
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory