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Vcpip1 Gene Detail
Summary
  • Symbol
    Vcpip1
  • Name
    valosin containing protein (p97)/p47 complex interacting protein 1
  • Synonyms
    5730421J18Rik, 5730538E15Rik, mKIAA1850, Vcip135
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917925
    NCBI Gene: 70675
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:9788847-9818607 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 2.08 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    569 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917925
 protein coding gene Chr1:9788847-9818607 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015827
 protein coding gene Chr1:6955091-6988059 (-)
A/J MGP_AJ_G0015809
 protein coding gene Chr1:7027862-7061193 (-)
AKR/J MGP_AKRJ_G0015768
 protein coding gene Chr1:6911535-6944011 (-)
BALB/cJ MGP_BALBcJ_G0015765
 protein coding gene Chr1:6765611-6794946 (-)
C3H/HeJ MGP_C3HHeJ_G0015599
 protein coding gene Chr1:6829841-6858829 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016219
 protein coding gene Chr1:7302428-7331301 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013940
 protein coding gene Chr1:5870833-5897538 (-)
CAST/EiJ MGP_CASTEiJ_G0015179
 protein coding gene Chr1:7019869-7050270 (-)
CBA/J MGP_CBAJ_G0015572
 protein coding gene Chr1:7441658-7470532 (-)
DBA/2J MGP_DBA2J_G0015671
 protein coding gene Chr1:6653082-6683050 (-)
FVB/NJ MGP_FVBNJ_G0015676
 protein coding gene Chr1:6568785-6597984 (-)
LP/J MGP_LPJ_G0015743
 protein coding gene Chr1:7175926-7208267 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015695
 protein coding gene Chr1:8099134-8135367 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016265
 protein coding gene Chr1:6813822-6845278 (-)
PWK/PhJ MGP_PWKPhJ_G0014963
 protein coding gene Chr1:6511114-6541680 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014743
 protein coding gene Chr1:6977651-7005097 (-)
WSB/EiJ MGP_WSBEiJ_G0015243
 protein coding gene Chr1:6843237-6873963 (-)



Homology
more
  • Human Ortholog
    VCPIP1, valosin containing protein interacting protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VCPIP1, valosin containing protein interacting protein 1
  • Synonyms
    DUBA3, VCIP135
  • Links
    NCBI Gene ID: 80124
    neXtProt AC: NX_Q96JH7
    UniProt: Q96JH7

  • Chr Location
    8q13.1; chr8:66628487-66667231 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Vcpip1 mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous knockout leads to chromosomal instability and premature aging.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 70675 NCBI Gene Model | MGI Sequence Detail 29761 C57BL/6J ±  kb
    transcript NM_173443 RefSeq | MGI Sequence Detail 9749 C57BL/6  
    polypeptide Q8CDG3 UniProt | EBI | MGI Sequence Detail 1220 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1917792
    References
    more
    • Summaries
      All 35
      Diseases 1
      Gene Ontology 7
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory