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Klhl30 Gene Detail
Summary
  • Symbol
    Klhl30
  • Name
    kelch-like 30
  • Synonyms
    4631423F02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918038
    NCBI Gene: 70788
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:91278795-91290126 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 46.09 cM, cytoband C5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    441 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918038
 protein coding gene Chr1:91278738-91290138 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016306
 protein coding gene Chr1:92893590-92904968 (+)
A/J MGP_AJ_G0016287
 protein coding gene Chr1:89544434-89555884 (+)
AKR/J MGP_AKRJ_G0016248
 protein coding gene Chr1:92205054-92226502 (+)
BALB/cJ MGP_BALBcJ_G0016243
 protein coding gene Chr1:89731453-89752913 (+)
C3H/HeJ MGP_C3HHeJ_G0016072
 protein coding gene Chr1:92426732-92438075 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016702
 protein coding gene Chr1:96455280-96466658 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014420
 protein coding gene Chr1:83802687-83814159 (+)
CAST/EiJ MGP_CASTEiJ_G0015657
 protein coding gene Chr1:91771277-91782685 (+)
CBA/J MGP_CBAJ_G0016048
 protein coding gene Chr1:99538142-99551782 (+)
DBA/2J MGP_DBA2J_G0016151
 protein coding gene Chr1:88776290-88787632 (+)
FVB/NJ MGP_FVBNJ_G0016150
 protein coding gene Chr1:87806943-87818529 (+)
LP/J MGP_LPJ_G0016222
 protein coding gene Chr1:94051055-94062831 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016175
 protein coding gene Chr1:102782373-102793774 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016742
 protein coding gene Chr1:92228835-92241283 (+)
PWK/PhJ MGP_PWKPhJ_G0015441
 protein coding gene Chr1:88189431-88200873 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015224
 protein coding gene Chr1:91153218-91164655 (+)
WSB/EiJ MGP_WSBEiJ_G0015715
 protein coding gene Chr1:92026705-92038051 (+)



Homology
more
  • Human Ortholog
    KLHL30, kelch like family member 30
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KLHL30, kelch like family member 30
  • Links
    NCBI Gene ID: 377007
    neXtProt AC: NX_Q0D2K2
    UniProt: Q0D2K2

  • Chr Location
    2q37.3; chr2:238138668-238152947 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    12
  • cDNA Data
    21
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70788 NCBI Gene Model | MGI Sequence Detail 11332 C57BL/6J ±  kb
transcript NM_027551 RefSeq | MGI Sequence Detail 3020 C57BL/6  
polypeptide Q8C3F7 UniProt | EBI | MGI Sequence Detail 581 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 21
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory