Mir205hg MGI Mouse Gene Detail - MGI:1918050

Symbol

Mir205hg
Name

Mir205 host gene
Synonyms

4631405K08Rik

Feature Type

lncRNA gene
IDs

MGI:1918050
NCBI Gene: 70800
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr1:193189546-193192482 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 97.82 cM
Mapping Data

1 experiment

SNPs within 2kb

166 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1918050	lncRNA gene	Chr1:193188768-193192518 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0005091	lincRNA gene	Chr1:200613839-200616775 (-)
A/J	MGP_AJ_G0005074	lincRNA gene	Chr1:192368627-192371565 (-)
AKR/J	MGP_AKRJ_G0005052	lincRNA gene	Chr1:198096176-198099105 (-)
BALB/cJ	MGP_BALBcJ_G0005055	lincRNA gene	Chr1:193063083-193066012 (-)
C3H/HeJ	MGP_C3HHeJ_G0005004	lincRNA gene	Chr1:198940764-198943701 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0005205	lincRNA gene	Chr1:206977653-206980589 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0004612	lincRNA gene	Chr1:183239184-183242125 (-)
CAST/EiJ	MGP_CASTEiJ_G0004951	lincRNA gene	Chr1:198517247-198520180 (-)
CBA/J	MGP_CBAJ_G0004994	lincRNA gene	Chr1:214626979-214629908 (-)
DBA/2J	MGP_DBA2J_G0005013	lincRNA gene	Chr1:191078137-191081066 (-)
FVB/NJ	MGP_FVBNJ_G0005034	lincRNA gene	Chr1:189207753-189210690 (-)
LP/J	MGP_LPJ_G0005092	lincRNA gene	Chr1:201791497-201794433 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0005017	lincRNA gene	Chr1:221267812-221270824 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0005212	lincRNA gene	Chr1:197914657-197917586 (-)
PWK/PhJ	MGP_PWKPhJ_G0004902	lincRNA gene	Chr1:190412748-190415732 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0004827	lincRNA gene	Chr1:196952423-196955317 (-)
WSB/EiJ	MGP_WSBEiJ_G0004998	lincRNA gene	Chr1:198212913-198215836 (-)

Human Ortholog

MIR205HG, MIR205 host gene

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR205HG, MIR205 host gene
Synonyms

LEADR, LINC00510, NPC-A-5
Links

HGNC:43562

NCBI Gene ID: 642587
Chr Location

1q32.2; chr1:209428817-209432848 (+) GRCh38

MGI Vertebrate Homology

Mir205hg stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR205HG
Gene Tree

Mir205hg

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Phenotype Summary

10 phenotypes from 2 alleles in 2 genetic backgrounds
2 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

3
Gene trapped

1
Targeted

2
Find Mice (IMSR)

1 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Mice homozygous for a knock-out allele exhibit reduced body size and weigth, slightly small thymus, and decreased serum levels of growth hormone and prolactin.

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All GO Annotations

7
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

818
Tissues

37
cDNA Data

4
Literature Summary

1

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

GEO

Expression Atlas

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All Sequences

25
RefSeq

1

Ensembl

ENSMUSG00000097850 (Evidence)
NCBI Gene

70800

Representative Sequences				Length	Strain/Species	Flank
	genomic	ENSMUSG00000097850	Ensembl Gene Model \| MGI Sequence Detail	2937	C57BL/6J	± kb
	transcript	ENSMUST00000180420	Ensembl \| MGI Sequence Detail	2112	Not Applicable

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All nucleic 15

cDNA 4

Primer pair 11

Microarray probesets 2

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MGI:6297108

Summaries

All 13

Developmental Gene Expression 1

Gene Ontology 1

Phenotypes 2
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:278363 Du Q, et al., MIR205HG Is a Long Noncoding RNA that Regulates Growth Hormone and Prolactin Production in the Anterior Pituitary. Dev Cell. 2019 May 20;49(4):618-631.e5

TSS for Mir205hg:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr15862	Chr1:193192510-193192524 (-)	-35 bp
Tssr15861	Chr1:193192477-193192485 (-)	1 bp
Tssr15860	Chr1:193192432-193192441 (-)	45 bp
Tssr15859	Chr1:193192388-193192397 (-)	89 bp
Tssr15858	Chr1:193192332-193192342 (-)	145 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24