Pgm2l1 MGI Mouse Gene Detail - MGI:1918224 - phosphoglucomutase 2-like 1

Symbol

Pgm2l1
Name

phosphoglucomutase 2-like 1
Synonyms

4931406N15Rik, BM32A

Feature Type

protein coding gene
IDs

MGI:1918224
NCBI Gene: 70974
Alliance

gene page
Transcription Start Sites

8 TSS

Sequence Map

Chr7:99876601-99928075 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 54.33 cM, cytoband F1
Mapping Data

3 experiments

SNPs within 2kb

1348 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1918224	protein coding gene	Chr7:99876471-99928079 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0032565	protein coding gene	Chr7:103095158-103151476 (+)
A/J	MGP_AJ_G0032539	protein coding gene	Chr7:100507482-100559970 (+)
AKR/J	MGP_AKRJ_G0032475	protein coding gene	Chr7:102896904-102949717 (+)
BALB/cJ	MGP_BALBcJ_G0032550	protein coding gene	Chr7:100179585-100234713 (+)
C3H/HeJ	MGP_C3HHeJ_G0032265	protein coding gene	Chr7:103264670-103319771 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0033048	protein coding gene	Chr7:107013091-107069556 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0030042	protein coding gene	Chr7:102912558-102962660 (+)
CAST/EiJ	MGP_CASTEiJ_G0031592	protein coding gene	Chr7:94810619-94866446 (+)
CBA/J	MGP_CBAJ_G0032232	protein coding gene	Chr7:110695783-110754947 (+)
DBA/2J	MGP_DBA2J_G0032383	protein coding gene	Chr7:98839571-98892092 (+)
FVB/NJ	MGP_FVBNJ_G0032340	protein coding gene	Chr7:98628369-98679591 (+)
LP/J	MGP_LPJ_G0032473	protein coding gene	Chr7:104453116-104508920 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0032373	protein coding gene	Chr7:112109354-112171199 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0033070	protein coding gene	Chr7:102164892-102220380 (+)
PWK/PhJ	MGP_PWKPhJ_G0031310	protein coding gene	Chr7:91942257-91995425 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0031153	protein coding gene	Chr7:89474526-89528678 (+)
WSB/EiJ	MGP_WSBEiJ_G0031709	protein coding gene	Chr7:102860696-102920052 (+)

Human Ortholog

PGM2L1, phosphoglucomutase 2 like 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

PGM2L1, phosphoglucomutase 2 like 1
Synonyms

BM32A, NEDHFS, PMMLP
Links

HGNC:20898

NCBI Gene ID: 283209

neXtProt AC: NX_Q6PCE3

UniProt: Q6PCE3
Chr Location

11q13.4; chr11:74330316-74398433 (-) GRCh38

MGI Vertebrate Homology

Pgm2l1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: PGM2L1
Gene Tree

Pgm2l1

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Phenotype Summary

12 phenotype references

All Mutations and Alleles

4
Chemically induced (other)

1
Endonuclease-mediated

1
Radiation induced

1
Targeted

1
Genomic Mutations

2 involving Pgm2l1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

25 strains or lines available

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All GO Annotations

7
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

898
Tissues

112
cDNA Data

20
Literature Summary

4

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase pgm2l1

ZFIN pgm2l1

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All Sequences

62
RefSeq

6
UniProt

4
CCDS

CCDS40035.1

Ensembl

ENSMUSG00000030729 (Evidence)
NCBI Gene

70974

			Length	Strain/Species	Flank
genomic	ENSMUSG00000030729	Ensembl Gene Model \| MGI Sequence Detail	51475	C57BL/6J	± kb
transcript	ENSMUST00000054436	Ensembl \| MGI Sequence Detail	4060	Not Applicable
polypeptide	ENSMUSP00000054782	Ensembl \| MGI Sequence Detail	621	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000012616 glucose 1,6-bisphosphate synthase

(term hierarchy)
EC

2.7.1.106
InterPro Domains

IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I

IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II

IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III

IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III

IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily
GlyGen

Q8CAA7 1 site, 1 O-linked glycan (1 site)

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All nucleic 20

cDNA 20

Microarray probesets 7

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MGI:2141998

Summaries

All 41

Developmental Gene Expression 4

Gene Ontology 6

Phenotypes 12
Earliest

J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
Latest

J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034

TSS for Pgm2l1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr68101	Chr7:99876518-99876591 (+)	-46 bp
Tssr68102	Chr7:99876669-99876711 (+)	89 bp
Tssr68103	Chr7:99876831-99876842 (+)	236 bp
Tssr68104	Chr7:99876845-99876913 (+)	278 bp
Tssr68105	Chr7:99876947-99876988 (+)	367 bp
Tssr68106	Chr7:99876990-99876995 (+)	392 bp
Tssr68107	Chr7:99884326-99884329 (+)	7,727 bp
Tssr68109	Chr7:99925855-99925857 (+)	49,255 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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