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Tektl1 Gene Detail
Summary
  • Symbol
    Tektl1
  • Name
    tektin like 1
  • Synonyms
    4931413A09Rik, Ccdc105
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918226
    NCBI Gene: 70976
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:78582760-78588899 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    244 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918226
protein coding gene Chr10:78582758-78623636 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017429
protein coding gene Chr10:79207448-79213587 (-)
A/J MGP_AJ_G0017407
protein coding gene Chr10:76452637-76463595 (-)
AKR/J MGP_AKRJ_G0017370
protein coding gene Chr10:78502253-78508388 (-)
BALB/cJ MGP_BALBcJ_G0017369
protein coding gene Chr10:76619022-76625165 (-)
C3H/HeJ MGP_C3HHeJ_G0017192
protein coding gene Chr10:78604454-78610571 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017825
protein coding gene Chr10:82000698-82006841 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015516
protein coding gene Chr10:72760564-72766714 (-)
CAST/EiJ MGP_CASTEiJ_G0016762
protein coding gene Chr10:78910483-78918461 (-)
CBA/J MGP_CBAJ_G0017164
protein coding gene Chr10:85131623-85140170 (-)
DBA/2J MGP_DBA2J_G0017272
protein coding gene Chr10:75683951-75692865 (-)
FVB/NJ MGP_FVBNJ_G0017264
protein coding gene Chr10:74864689-74870831 (-)
LP/J MGP_LPJ_G0017343
protein coding gene Chr10:79663038-79670189 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017291
protein coding gene Chr10:87106989-87113124 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017867
protein coding gene Chr10:78548174-78554316 (-)
PWK/PhJ MGP_PWKPhJ_G0016544
protein coding gene Chr10:75571760-75579919 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016329
protein coding gene Chr10:77747138-77753223 (-)
WSB/EiJ MGP_WSBEiJ_G0016822
protein coding gene Chr10:78536412-78543427 (-)



Homology
more
  • Human Ortholog
    TEKTL1, tektin like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TEKTL1, tektin like 1
  • Synonyms
    CCDC105
  • Links
    NCBI Gene ID: 126402
    neXtProt AC: NX_Q8IYK2
    UniProt: Q8IYK2

  • Chr Location
    19p13.12; chr19:15010726-15023276 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Male mice homozygous for a null allele exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000078442 Ensembl Gene Model | MGI Sequence Detail 6140 C57BL/6J ±  kb
    transcript ENSMUST00000105383 Ensembl | MGI Sequence Detail 1714 Not Applicable  
    polypeptide ENSMUSP00000101022 Ensembl | MGI Sequence Detail 499 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:7482283
    References
    more
    • Summaries
      All 30
      Gene Ontology 3
      Phenotypes 8
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:348447 Nguyen TTT, et al., Gene-deficient mouse model established by CRISPR/Cas9 system reveals 15 reproductive organ-enriched genes dispensable for male fertility. Frontiers in Cell and Developmental Biology. 2024;12

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    12/10/2024
    MGI 6.24
    The Jackson Laboratory