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Cdkl1 Gene Detail
Summary
  • Symbol
    Cdkl1
  • Name
    cyclin dependent kinase like 1
  • Synonyms
    4933411O17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918341
    NCBI Gene: 71091
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:69793622-69838041 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 28.94 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1292 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918341
 protein coding gene Chr12:69791944-69838057 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019801
 protein coding gene Chr12:69458324-69504542 (-)
A/J MGP_AJ_G0019759
 protein coding gene Chr12:66869083-66913308 (-)
AKR/J MGP_AKRJ_G0019735
 protein coding gene Chr12:68872778-68917075 (-)
BALB/cJ MGP_BALBcJ_G0019739
 protein coding gene Chr12:67331388-67377002 (-)
C3H/HeJ MGP_C3HHeJ_G0019545
 protein coding gene Chr12:69340780-69386543 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020191
 protein coding gene Chr12:71682401-71729236 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017811
 protein coding gene Chr12:64406653-64453384 (-)
CAST/EiJ MGP_CASTEiJ_G0019096
 protein coding gene Chr12:64091474-64139323 (-)
CBA/J MGP_CBAJ_G0019514
 protein coding gene Chr12:74332523-74378569 (-)
DBA/2J MGP_DBA2J_G0019630
 protein coding gene Chr12:66779981-66826523 (-)
FVB/NJ MGP_FVBNJ_G0019617
 protein coding gene Chr12:65681635-65727306 (-)
LP/J MGP_LPJ_G0019702
 protein coding gene Chr12:69412362-69459041 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019656
 protein coding gene Chr12:77642735-77693214 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020226
 protein coding gene Chr12:68353243-68399161 (-)
PWK/PhJ MGP_PWKPhJ_G0018861
 protein coding gene Chr12:61051663-61103006 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018656
 protein coding gene Chr12:62723268-62770882 (-)
WSB/EiJ MGP_WSBEiJ_G0019147
 protein coding gene Chr12:68976665-69023066 (-)



Homology
more
  • Human Ortholog
    CDKL1, cyclin dependent kinase like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDKL1, cyclin dependent kinase like 1
  • Synonyms
    KKIALRE, P42
  • Links
    NCBI Gene ID: 8814
    neXtProt AC: NX_Q00532
    UniProt: Q00532

  • Chr Location
    14q21.3; chr14:50326265-50416461 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    2
  • cDNA Data
    12
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020990 Ensembl Gene Model | MGI Sequence Detail 44420 C57BL/6J ±  kb
transcript ENSMUST00000021377 Ensembl | MGI Sequence Detail 1689 Not Applicable  
polypeptide ENSMUSP00000021377 Ensembl | MGI Sequence Detail 352 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 2
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 9
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory