About   Help   FAQ
Flacc1 Gene Detail
Summary
  • Symbol
    Flacc1
  • Name
    flagellum associated containing coiled-coil domains 1
  • Synonyms
    4933405P16Rik, 4933425F06Rik, Als2cr12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918359
    NCBI Gene: 108812
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:58696085-58735167 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 29.15 cM, cytoband C2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1322 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918359
 protein coding gene Chr1:58686062-58735167 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016056
 protein coding gene Chr1:58557113-58841681 (-)
A/J MGP_AJ_G0016039
 protein coding gene Chr1:56501922-56550025 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0015994
 protein coding gene Chr1:56538153-56839109 (-)
C3H/HeJ MGP_C3HHeJ_G0015826
 protein coding gene Chr1:58299483-58637683 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016447
 protein coding gene Chr1:60908538-60949249 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0015408
 protein coding gene Chr1:57510211-57556553 (+)
CBA/J MGP_CBAJ_G0015798
 protein coding gene Chr1:62725796-63058589 (-)
DBA/2J MGP_DBA2J_G0015899
 protein coding gene Chr1:55916242-56217695 (-)
FVB/NJ MGP_FVBNJ_G0015901
 protein coding gene Chr1:55229919-55303658 (-)
LP/J MGP_LPJ_G0015971
 protein coding gene Chr1:59443368-59721634 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015921
 protein coding gene Chr1:65687567-65765902 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016494
 protein coding gene Chr1:58011637-58285716 (-)
PWK/PhJ MGP_PWKPhJ_G0015196
 protein coding gene Chr1:55324814-55552341 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014977
 protein coding gene Chr1:57746030-57768104 (-)
WSB/EiJ MGP_WSBEiJ_G0015471
 protein coding gene Chr1:57719293-57748980 (-)



Homology
more
  • Human Ortholog
    FLACC1, flagellum associated containing coiled-coil domains 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FLACC1, flagellum associated containing coiled-coil domains 1
  • Synonyms
    ALS2CR12
  • Links
    NCBI Gene ID: 130540
    neXtProt AC: NX_Q96Q35
    UniProt: Q96Q35

  • Chr Location
    2q33.1; chr2:201288271-201364289 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit normal reproduction.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 108812 NCBI Gene Model | MGI Sequence Detail 39083 C57BL/6J ±  kb
transcript NM_175370 RefSeq | MGI Sequence Detail 1575 C57BL/6  
polypeptide Q8BVM7 UniProt | EBI | MGI Sequence Detail 383 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000003974 flagellum-associated coiled-coil domain-containing protein 1
    (term hierarchy)
  • InterPro Domains
    IPR026674 Flagellum-associated coiled-coil domain-containing protein 1
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
Other
Accession IDs
less
MGI:1921656, MGI:6285795
References
more
  • Summaries
    All 30
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:298518 Chotiner JY, et al., FLACC1 is testis-specific but dispensable for fertility in mice. Mol Reprod Dev. 2020 Nov 6;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory