Dydc2 Gene Detail

Summary

• Symbol
  Dydc2
• Name
  DPY30 domain containing 2
• Synonyms
  4933428D01Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1918450
  NCBI Gene: 71200
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr14:40771074-40791165 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, 22.36 cM, cytoband C1
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  428 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1918450	protein coding gene	Chr14:40770573-40795014 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0021194	protein coding gene	Chr14:34685971-34699142 (-)
A/J	MGP_AJ_G0021142	protein coding gene	Chr14:33339385-33351824 (-)
AKR/J	MGP_AKRJ_G0021119	protein coding gene	Chr14:34701224-34715580 (-)
BALB/cJ	MGP_BALBcJ_G0021146	protein coding gene	Chr14:33555692-33571553 (-)
C3H/HeJ	MGP_C3HHeJ_G0020929	protein coding gene	Chr14:34664881-34678639 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0021578	protein coding gene	Chr14:36076643-36093789 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019140	protein coding gene	Chr14:32967174-32978464 (-)
CAST/EiJ	MGP_CASTEiJ_G0020454	protein coding gene	Chr14:34432735-34443606 (-)
CBA/J	MGP_CBAJ_G0020895	protein coding gene	Chr14:37310269-37324200 (-)
DBA/2J	MGP_DBA2J_G0021018	protein coding gene	Chr14:33293939-33305652 (-)
FVB/NJ	MGP_FVBNJ_G0021002	protein coding gene	Chr14:33229002-33249108 (-)
LP/J	MGP_LPJ_G0021087	protein coding gene	Chr14:34919088-34932322 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021028	protein coding gene	Chr14:36932206-36945355 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021611	protein coding gene	Chr14:34484622-34497457 (-)
PWK/PhJ	MGP_PWKPhJ_G0020202	protein coding gene	Chr14:32769691-32781571 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0020026	protein coding gene	Chr14:34113945-34126315 (-)
WSB/EiJ	MGP_WSBEiJ_G0020509	protein coding gene	Chr14:34598644-34615522 (-)

Homology

• Human Ortholog
  DYDC2, DPY30 domain containing 2

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  DYDC2, DPY30 domain containing 2
  
• Links
  HGNC:23468

  NCBI Gene ID: 84332

  neXtProt AC: NX_Q96IM9

  UniProt: Q96IM9

  
  
• Chr Location
  10q23.1; chr10:80344745-80368073 (+)  GRCh38

---

• MGI Vertebrate Homology
  Dydc2 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: DYDC2
• Gene Tree
  Dydc2
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  83 phenotype references
  

• All Mutations and Alleles
  7
• Endonuclease-mediated
  2
• Gene trapped
  2
• Targeted
  2
• Transgenic
  1
• Genomic Mutations
  1 involving Dydc2
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  9 strains or lines available

Expression

• Assay Results
  714
• Tissues
  1
• cDNA Data
  7
• Literature Summary
  1

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  41
• RefSeq
  14
• UniProt
  1
• CCDS
  CCDS26958.1

• Ensembl
  ENSMUSG00000021791 (Evidence)
• NCBI Gene
  71200

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000021791	Ensembl Gene Model | MGI Sequence Detail	20092	C57BL/6J
transcript	ENSMUST00000022316	Ensembl | MGI Sequence Detail	818	Not Applicable
polypeptide	ENSMUSP00000022316	Ensembl | MGI Sequence Detail	139	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• PDB
  8WZB, 8X2U
• InterPro Domains
  IPR049630 DPY30 domain-containing protein-like, dimerization/docking domain
  IPR007858 Dpy-30 motif
  IPR037856 Sdc1/DPY30

Molecular
Reagents

• All nucleic 9

  cDNA 7

  Primer pair 2

  
  

  Microarray probesets 3

References

• Summaries
  All 103

  Developmental Gene Expression 1

  Phenotypes 83
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:359170 Vadisiute A, et al., Glial cells undergo rapid changes following acute chemogenetic manipulation of cortical layer 5 projection neurons. Commun Biol. 2024 Oct 9;7(1):1286

TSS for Dydc2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr128209	Chr14:40791150-40791169 (-)	5 bp