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Nudt4 Gene Detail
Summary
  • Symbol
    Nudt4
  • Name
    nudix hydrolase 4
  • Synonyms
    4933436C10Rik, DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, nudix (nucleoside diphosphate linked moiety X)-type motif 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918457
    NCBI Gene: 71207
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:95382869-95400008 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 49.42 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    567 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918457
 protein coding gene Chr10:95382869-95400008 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017671
 protein coding gene Chr10:97131443-97150081 (-)
A/J MGP_AJ_G0017650
 protein coding gene Chr10:93692791-93710180 (-)
AKR/J MGP_AKRJ_G0017609
 protein coding gene Chr10:96376156-96394659 (-)
BALB/cJ MGP_BALBcJ_G0017614
 protein coding gene Chr10:93965266-93982339 (-)
C3H/HeJ MGP_C3HHeJ_G0017436
 protein coding gene Chr10:96365999-96381796 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018071
 protein coding gene Chr10:100324655-100343413 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015752
 protein coding gene Chr10:89249469-89266724 (-)
CAST/EiJ MGP_CASTEiJ_G0017000
 protein coding gene Chr10:96384727-96401684 (-)
CBA/J MGP_CBAJ_G0017406
 protein coding gene Chr10:104465187-104490547 (-)
DBA/2J MGP_DBA2J_G0017512
 protein coding gene Chr10:92783932-92801310 (-)
FVB/NJ MGP_FVBNJ_G0017504
 protein coding gene Chr10:92035350-92052520 (-)
LP/J MGP_LPJ_G0017586
 protein coding gene Chr10:97740734-97759544 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017534
 protein coding gene Chr10:105632285-105650683 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018107
 protein coding gene Chr10:96277100-96294216 (-)
PWK/PhJ MGP_PWKPhJ_G0016783
 protein coding gene Chr10:92890203-92907306 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016571
 protein coding gene Chr10:95116439-95134634 (-)
WSB/EiJ MGP_WSBEiJ_G0017060
 protein coding gene Chr10:96255997-96271867 (-)



Homology
more
  • Human Ortholog
    NUDT4, nudix hydrolase 4
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NUDT4, nudix hydrolase 4
  • Synonyms
    DIPP2, DIPP2alpha, DIPP-2B, DIPP2beta, HDCMB47P, NUDT4B
  • Links
    NCBI Gene ID: 11163
    neXtProt AC: NX_A0A024RBG1, NX_Q9NZJ9
    UniProt: Q9NZJ9

  • Chr Location
    12q22; chr12:93377883-93408146 (+)  GRCh38
  • Human Ortholog
    NUDT4B, nudix hydrolase 4B
  • Synonyms
    DIPP-2B, NUDT4P1
  • Links
    NCBI Gene ID: 440672
    UniProt: A0A024RBG1

  • Chr Location
    1q21.2; chr1:148748774-148752415 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
  • All Mutations and Alleles
    25
  • Chemically induced (other)
    1
  • Gene trapped
    20
  • Targeted
    3
  • Transposon induced
    1
  • Genomic Mutations
    2 involving Nudt4
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    12 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71207 NCBI Gene Model | MGI Sequence Detail 17140 C57BL/6J ±  kb
transcript NM_001358996 RefSeq | MGI Sequence Detail 3213 C57BL/6  
polypeptide Q8R2U6 UniProt | EBI | MGI Sequence Detail 179 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 5
References
more
  • Summaries
    All 43
    Gene Ontology 7
    Phenotypes 17
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory