Tchhl1 MGI Mouse Gene Detail - MGI:1918575

Symbol

Tchhl1
Name

trichohyalin-like 1
Synonyms

5430400H23Rik, S100a17, Thhl1

Feature Type

protein coding gene
IDs

MGI:1918575
NCBI Gene: 71325
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr3:93376061-93379287 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 40.51 cM, cytoband F2
Mapping Data

3 experiments

SNPs within 2kb

182 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1918575	protein coding gene	Chr3:93376061-93379287 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0027535	protein coding gene	Chr3:93959936-93963162 (+)
A/J	MGP_AJ_G0027500	protein coding gene	Chr3:91046179-91049405 (+)
AKR/J	MGP_AKRJ_G0027468	protein coding gene	Chr3:93146010-93149236 (+)
BALB/cJ	MGP_BALBcJ_G0027509	protein coding gene	Chr3:90800589-90803815 (+)
C3H/HeJ	MGP_C3HHeJ_G0027247	protein coding gene	Chr3:93366060-93369286 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0027952	protein coding gene	Chr3:97533726-97536952 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025302	protein coding gene	Chr3:87639961-87643172 (+)
CAST/EiJ	MGP_CASTEiJ_G0026695	protein coding gene	Chr3:92806434-92809653 (+)
CBA/J	MGP_CBAJ_G0027223	protein coding gene	Chr3:100939811-100943037 (+)
DBA/2J	MGP_DBA2J_G0027360	protein coding gene	Chr3:90352400-90355626 (+)
FVB/NJ	MGP_FVBNJ_G0027329	protein coding gene	Chr3:88474687-88477913 (+)
LP/J	MGP_LPJ_G0027470	protein coding gene	Chr3:95213426-95216652 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027355	protein coding gene	Chr3:107176784-107180018 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028011	protein coding gene	Chr3:92870262-92873488 (+)
PWK/PhJ	MGP_PWKPhJ_G0026424	protein coding gene	Chr3:90213391-90216618 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0026244	protein coding gene	Chr3:91224963-91228183 (+)
WSB/EiJ	MGP_WSBEiJ_G0026778	protein coding gene	Chr3:93254185-93257411 (+)

Human Ortholog

TCHHL1, trichohyalin like 1

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TCHHL1, trichohyalin like 1
Synonyms

S100A17, THHL1
Links

HGNC:31796

NCBI Gene ID: 126637

neXtProt AC: NX_Q5QJ38

UniProt: Q5QJ38
Chr Location

1q21.3; chr1:152084141-152089064 (-) GRCh38

MGI Vertebrate Homology

Tchhl1 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: TCHHL1
Gene Tree

Tchhl1

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References

1 with disease annotations

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

7
Chemically induced (other)

1
Endonuclease-mediated

4
Radiation induced

1
Targeted

1
Genomic Mutations

2 involving Tchhl1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

25 strains or lines available

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All GO Annotations

2
GO References

1

Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

710
Tissues

1
cDNA Data

26
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

30
RefSeq

2
UniProt

1
CCDS

CCDS17582.1

Ensembl

ENSMUSG00000027908 (Evidence)
NCBI Gene

71325

			Length	Strain/Species	Flank
genomic	71325	NCBI Gene Model \| MGI Sequence Detail	3227	C57BL/6J	± kb
transcript	NM_027762	RefSeq \| MGI Sequence Detail	2066	C57BL/6
polypeptide	Q9D3P1	UniProt \| EBI \| MGI Sequence Detail	638	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000016190 trichohyalin-like protein 1

(term hierarchy)
InterPro Domains

IPR002048 EF-hand domain

IPR011992 EF-hand domain pair

IPR034325 S-100

IPR013787 S100/CaBP-9k-type, calcium binding, subdomain

IPR042937 Trichohyalin-like protein 1

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All nucleic 27

cDNA 26

Primer pair 1

Microarray probesets 3

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MGI:2139596

Summaries

All 35

Developmental Gene Expression 2

Diseases 1

Gene Ontology 1

Phenotypes 10
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Tchhl1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr30408	Chr3:93376058-93376063 (+)	0 bp
Tssr30409	Chr3:93377986-93377994 (+)	1,929 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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