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Rbks Gene Detail
Summary
  • Symbol
    Rbks
  • Name
    ribokinase
  • Synonyms
    5230400M11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918586
    NCBI Gene: 71336
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:31781783-31854971 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 17.27 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1921 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918586
 protein coding gene Chr5:31781783-31855042 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029431
 protein coding gene Chr5:29655456-29733169 (-)
A/J MGP_AJ_G0029397
 protein coding gene Chr5:28698465-28771583 (-)
AKR/J MGP_AKRJ_G0029347
 protein coding gene Chr5:29849678-29926552 (-)
BALB/cJ MGP_BALBcJ_G0029408
 protein coding gene Chr5:29228679-29301634 (-)
C3H/HeJ MGP_C3HHeJ_G0029129
 protein coding gene Chr5:29871807-29946346 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029861
 protein coding gene Chr5:31473188-31545386 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027099
 protein coding gene Chr5:26308000-26389120 (-)
CAST/EiJ MGP_CASTEiJ_G0028539
 protein coding gene Chr5:28910527-28993080 (-)
CBA/J MGP_CBAJ_G0029097
 protein coding gene Chr5:32121174-32198823 (-)
DBA/2J MGP_DBA2J_G0029246
 protein coding gene Chr5:28858706-28949317 (-)
FVB/NJ MGP_FVBNJ_G0029204
 protein coding gene Chr5:28279031-28352991 (-)
LP/J MGP_LPJ_G0029331
 protein coding gene Chr5:30103373-30177593 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029233
 protein coding gene Chr5:32940868-33014940 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029895
 protein coding gene Chr5:29348068-29422225 (-)
PWK/PhJ MGP_PWKPhJ_G0028264
 protein coding gene Chr5:28018055-28093989 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028095
 protein coding gene Chr5:28816778-28894279 (-)
WSB/EiJ MGP_WSBEiJ_G0028620
 protein coding gene Chr5:29422056-29497612 (-)



Homology
more
  • Human Ortholog
    RBKS, ribokinase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RBKS, ribokinase
  • Synonyms
    RBSK, RK
  • Links
    NCBI Gene ID: 64080
    neXtProt AC: NX_Q9H477
    UniProt: Q9H477

  • Chr Location
    2p23.2; chr2:27781379-27890681 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    32 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are viable, fertile and overtly normal but show enhanced gut motility due to disrupted ribose homeostasis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    806
  • Tissues
    97
  • cDNA Data
    21
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000029136 Ensembl Gene Model | MGI Sequence Detail 73189 C57BL/6J ±  kb
    transcript ENSMUST00000031018 Ensembl | MGI Sequence Detail 1042 Not Applicable  
    polypeptide ENSMUSP00000031018 Ensembl | MGI Sequence Detail 323 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 22
      cDNA 21
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2140842
    References
    more
    • Summaries
      All 65
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 10
      Phenotypes 32
    • Earliest
      J:322975 HIATT HH, Glycogen formation via the pentose phosphate pathway in mice in vivo. J Biol Chem. 1957 Feb;224(2):851-9
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory