Col24a1 MGI Mouse Gene Detail - MGI:1918605 - collagen, type XXIV, alpha 1

Symbol

Col24a1
Name

collagen, type XXIV, alpha 1
Synonyms

5430404K19Rik

Feature Type

protein coding gene
IDs

MGI:1918605
NCBI Gene: 71355
Alliance

gene page
Transcription Start Sites

4 TSS

Sequence Map

Chr3:144998233-145257766 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 69.42 cM, cytoband H3
Mapping Data

3 experiments

SNPs within 2kb

8618 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1918605	protein coding gene	Chr3:144998233-145257768 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0027959	protein coding gene	Chr3:148695108-148981267 (+)
A/J	MGP_AJ_G0027918	protein coding gene	Chr3:143405885-143674062 (+)
AKR/J	MGP_AKRJ_G0027884	protein coding gene	Chr3:147203358-147474891 (+)
BALB/cJ	MGP_BALBcJ_G0027930	protein coding gene	Chr3:143221478-143484099 (+)
C3H/HeJ	MGP_C3HHeJ_G0027660	protein coding gene	Chr3:147577601-147848964 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0028373	protein coding gene	Chr3:153804062-154070530 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025712	protein coding gene	Chr3:138489378-138754513 (+)
CAST/EiJ	MGP_CASTEiJ_G0027113	protein coding gene	Chr3:147523287-147808154 (+)
CBA/J	MGP_CBAJ_G0027635	protein coding gene	Chr3:159144915-159437659 (+)
DBA/2J	MGP_DBA2J_G0027775	protein coding gene	Chr3:142551891-142826031 (+)
FVB/NJ	MGP_FVBNJ_G0027742	protein coding gene	Chr3:139964870-140231217 (+)
LP/J	MGP_LPJ_G0027886	protein coding gene	Chr3:150095212-150368206 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027775	protein coding gene	Chr3:167476055-167758688 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028432	protein coding gene	Chr3:146805440-147078878 (+)
PWK/PhJ	MGP_PWKPhJ_G0026836	protein coding gene	Chr3:142398686-142662105 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0026664	protein coding gene	Chr3:144977032-145251185 (+)
WSB/EiJ	MGP_WSBEiJ_G0027193	protein coding gene	Chr3:147766667-148037851 (+)

Human Ortholog

COL24A1, collagen type XXIV alpha 1 chain

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

COL24A1, collagen type XXIV alpha 1 chain
Links

HGNC:20821

NCBI Gene ID: 255631

neXtProt AC: NX_Q17RW2

UniProt: Q17RW2
Chr Location

1p22.3; chr1:85729233-86156984 (-) GRCh38

MGI Vertebrate Homology

Col24a1 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: COL24A1
Gene Tree

Col24a1

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References

1 with disease annotations

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
11 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

6
Endonuclease-mediated

2
Radiation induced

1
Targeted

3
Genomic Mutations

1 involving Col24a1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

80 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

9
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

826
Tissues

49
cDNA Data

8
Literature Summary

3

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase col24a1

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All Sequences

52
RefSeq

14
UniProt

5
CCDS

CCDS17892.1

Ensembl

ENSMUSG00000028197 (Evidence)
NCBI Gene

71355

			Length	Strain/Species	Flank
genomic	ENSMUSG00000028197	Ensembl Gene Model \| MGI Sequence Detail	259534	C57BL/6J	± kb
transcript	ENSMUST00000029848	Ensembl \| MGI Sequence Detail	7143	Not Applicable
polypeptide	ENSMUSP00000029848	Ensembl \| MGI Sequence Detail	1733	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000005708 collagen alpha-1(XXIV) chain

(term hierarchy)
InterPro Domains

IPR050149 Collagen superfamily

IPR008160 Collagen triple helix repeat

IPR013320 Concanavalin A-like lectin/glucanase domain superfamily

IPR000885 Fibrillar collagen, C-terminal

IPR048287 Thrombospondin-like, N-terminal domain
GlyGen

Q30D77 4 sites

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All nucleic 12

Genomic 2

cDNA 8

Primer pair 1

Other 1

Microarray probesets 2

Summaries

All 38

Developmental Gene Expression 3

Diseases 1

Gene Ontology 5

Phenotypes 11
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Col24a1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr32284	Chr3:144998270-144998297 (+)	51 bp
Tssr32285	Chr3:144998298-144998330 (+)	81 bp
Tssr32286	Chr3:144998458-144998475 (+)	234 bp
Tssr32287	Chr3:144998477-144998537 (+)	274 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24