About   Help   FAQ
Gpatch8 Gene Detail
Summary
  • Symbol
    Gpatch8
  • Name
    G patch domain containing 8
  • Synonyms
    5430405G24Rik, ENSMUSG00000075516, Fbm1, Gpatc8, mKIAA0553
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918667
    NCBI Gene: 237943
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:102366741-102447218 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 66.31 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1351 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918667
 protein coding gene Chr11:102366737-102447218 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019238
 protein coding gene Chr11:105454176-105537833 (-)
A/J MGP_AJ_G0019206
 protein coding gene Chr11:101003930-101087607 (-)
AKR/J MGP_AKRJ_G0019175
 protein coding gene Chr11:104123232-104214441 (-)
BALB/cJ MGP_BALBcJ_G0019180
 protein coding gene Chr11:101490407-101571660 (-)
C3H/HeJ MGP_C3HHeJ_G0018989
 protein coding gene Chr11:104333481-104423538 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019629
 protein coding gene Chr11:108742452-108832833 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017255
 protein coding gene Chr11:98430284-98508693 (-)
CAST/EiJ MGP_CASTEiJ_G0018543
 protein coding gene Chr11:105323147-105410650 (-)
CBA/J MGP_CBAJ_G0018958
 protein coding gene Chr11:113231164-113320264 (-)
DBA/2J MGP_DBA2J_G0019070
 protein coding gene Chr11:100522282-100602609 (-)
FVB/NJ MGP_FVBNJ_G0019060
 protein coding gene Chr11:100052513-100139985 (-)
LP/J MGP_LPJ_G0019139
 protein coding gene Chr11:105979646-106070963 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019091
 protein coding gene Chr11:112730390-112811963 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019667
 protein coding gene Chr11:104496461-104581402 (-)
PWK/PhJ MGP_PWKPhJ_G0018306
 protein coding gene Chr11:101587314-101666892 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018098
 protein coding gene Chr11:104248979-104335666 (-)
WSB/EiJ MGP_WSBEiJ_G0018592
 protein coding gene Chr11:104491558-104576812 (-)



Homology
more
  • Human Ortholog
    GPATCH8, G-patch domain containing 8
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPATCH8, G-patch domain containing 8
  • Synonyms
    GPATC8, KIAA0553
  • Links
    NCBI Gene ID: 23131
    neXtProt AC: NX_Q9UKJ3
    UniProt: Q9UKJ3

  • Chr Location
    17q21.31; chr17:44395281-44503430 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    11
  • cDNA Data
    102
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034621 Ensembl Gene Model | MGI Sequence Detail 80478 C57BL/6J ±  kb
transcript ENSMUST00000143842 Ensembl | MGI Sequence Detail 6871 Not Applicable  
polypeptide ENSMUSP00000120649 Ensembl | MGI Sequence Detail 1505 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 104
    cDNA 104

    Microarray probesets 10
Other
Accession IDs
less
MGI:2144385, MGI:3642003, MGI:894666
References
more
  • Summaries
    All 45
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 15
  • Earliest
    J:41036 Kai N, et al., Molecular cloning of Fyn-associated molecules in the mouse central nervous system. J Neurosci Res. 1997 Jun 1;48(5):407-24
  • Latest
    J:352160 Benbarche S, et al., GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies. Mol Cell. 2024 May 16;84(10):1886-1903.e10
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory