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Cyp2u1 Gene Detail
Summary
  • Symbol
    Cyp2u1
  • Name
    cytochrome P450, family 2, subfamily u, polypeptide 1
  • Synonyms
    8430436A10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918769
    NCBI Gene: 71519
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:131084140-131097806 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 60.89 cM, cytoband H1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    522 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918769
 protein coding gene Chr3:131082090-131097806 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027887
 protein coding gene Chr3:134085568-134101534 (-)
A/J MGP_AJ_G0027845
 protein coding gene Chr3:129357799-129374286 (-)
AKR/J MGP_AKRJ_G0027810
 protein coding gene Chr3:132729200-132745769 (-)
BALB/cJ MGP_BALBcJ_G0027858
 protein coding gene Chr3:129215396-129230950 (-)
C3H/HeJ MGP_C3HHeJ_G0027587
 protein coding gene Chr3:133135519-133150145 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028301
 protein coding gene Chr3:138808684-138825435 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025639
 protein coding gene Chr3:124878230-124893558 (-)
CAST/EiJ MGP_CASTEiJ_G0027043
 protein coding gene Chr3:132855367-132870025 (-)
CBA/J MGP_CBAJ_G0027563
 protein coding gene Chr3:143472068-143489388 (-)
DBA/2J MGP_DBA2J_G0027703
 protein coding gene Chr3:128562885-128577756 (-)
FVB/NJ MGP_FVBNJ_G0027670
 protein coding gene Chr3:126142110-126157313 (-)
LP/J MGP_LPJ_G0027813
 protein coding gene Chr3:135562677-135577278 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027701
 protein coding gene Chr3:151405078-151420840 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028359
 protein coding gene Chr3:132412109-132426506 (-)
PWK/PhJ MGP_PWKPhJ_G0026767
 protein coding gene Chr3:128307050-128322101 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026592
 protein coding gene Chr3:130455605-130470376 (-)
WSB/EiJ MGP_WSBEiJ_G0027122
 protein coding gene Chr3:133149693-133164112 (-)



Homology
more
  • Human Ortholog
    CYP2U1, cytochrome P450 family 2 subfamily U member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2U1, cytochrome P450 family 2 subfamily U member 1
  • Synonyms
    P450TEC, SPG49, SPG56
  • Links
    NCBI Gene ID: 113612
    neXtProt AC: NX_Q7Z449
    UniProt: Q7Z449

  • Chr Location
    4q25; chr4:107931549-107953461 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CYP2U1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    848
  • Tissues
    131
  • cDNA Data
    4
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 71519 NCBI Gene Model | MGI Sequence Detail 13667 C57BL/6J ±  kb
    transcript NM_027816 RefSeq | MGI Sequence Detail 2331 Not Specified  
    polypeptide Q9CX98 UniProt | EBI | MGI Sequence Detail 530 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      Genomic 2
      cDNA 4
      Primer pair 2

      Microarray probesets 5
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 5
      Diseases 1
      Gene Ontology 7
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:348785 Zhang D, et al., Maternal Ezh1/2 deficiency impairs the function of mitochondria in mouse oocytes and early embryos. J Cell Physiol. 2024 Mar 26;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory