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Slc16a7 Gene Detail
Summary
  • Symbol
    Slc16a7
  • Name
    solute carrier family 16 (monocarboxylic acid transporters), member 7
  • Synonyms
    4921534N07Rik, 9030411M13Rik, D630004K10Rik, MCT2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1330284
    NCBI Gene: 20503
  • Alliance
    gene page
  • Transcription Start Sites
    24 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:125055139-125225334 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 72.31 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6184 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330284
 protein coding gene Chr10:125055139-125225455 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017794
 protein coding gene Chr10:128709034-128810892 (-)
A/J MGP_AJ_G0017769
 protein coding gene Chr10:123563677-123663343 (-)
AKR/J MGP_AKRJ_G0017732
 protein coding gene Chr10:127214887-127318150 (-)
BALB/cJ MGP_BALBcJ_G0017733
 protein coding gene Chr10:123970179-124074730 (-)
C3H/HeJ MGP_C3HHeJ_G0017557
 protein coding gene Chr10:127392003-127496763 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018188
 protein coding gene Chr10:133043536-133152251 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015868
 protein coding gene Chr10:117686591-117782919 (-)
CAST/EiJ MGP_CASTEiJ_G0017117
 protein coding gene Chr10:127927089-128031379 (-)
CBA/J MGP_CBAJ_G0017526
 protein coding gene Chr10:138482969-138595627 (-)
DBA/2J MGP_DBA2J_G0017632
 protein coding gene Chr10:122667513-122767056 (-)
FVB/NJ MGP_FVBNJ_G0017627
 protein coding gene Chr10:121606691-121705038 (-)
LP/J MGP_LPJ_G0017706
 protein coding gene Chr10:129231658-129349010 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017655
 protein coding gene Chr10:141161331-141270171 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018228
 protein coding gene Chr10:127267770-127367863 (-)
PWK/PhJ MGP_PWKPhJ_G0016902
 protein coding gene Chr10:122821561-122921578 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016694
 protein coding gene Chr10:126273548-126374477 (-)
WSB/EiJ MGP_WSBEiJ_G0017178
 protein coding gene Chr10:127457411-127561940 (-)



Homology
more
  • Human Ortholog
    SLC16A7, solute carrier family 16 member 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC16A7, solute carrier family 16 member 7
  • Synonyms
    MCT2
  • Links
    NCBI Gene ID: 9194
    neXtProt AC: NX_O60669
    UniProt: O60669

  • Chr Location
    12q14.1; chr12:59596029-59789855 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    36
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    906
  • Tissues
    165
  • cDNA Data
    13
  • Literature Summary
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020102 Ensembl Gene Model | MGI Sequence Detail 170196 C57BL/6J ±  kb
transcript ENSMUST00000211781 Ensembl | MGI Sequence Detail 10981 Not Applicable  
polypeptide ENSMUSP00000147968 Ensembl | MGI Sequence Detail 484 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    Genomic 1
    cDNA 13
    Primer pair 4

    Microarray probesets 6
Other
Accession IDs
less
MGI:1918785, MGI:2143596, MGI:2444072
References
more
  • Summaries
    All 49
    Developmental Gene Expression 12
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:46855 Pellerin L, et al., Expression of monocarboxylate transporter mRNAs in mouse brain: support for a distinct role of lactate as an energy substrate for the neonatal vs. adult brain. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3990-5
  • Latest
    J:351407 Braga A, et al., Astrocytic metabolic control of orexinergic activity in the lateral hypothalamus regulates sleep and wake architecture. Nat Commun. 2024 Jul 16;15(1):5979
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory