Fam110c MGI Mouse Gene Detail - MGI:1918813 - family with sequence similarity 110, member C

Symbol

Fam110c
Name

family with sequence similarity 110, member C
Synonyms

9030611O19Rik

Feature Type

protein coding gene
IDs

MGI:1918813
NCBI Gene: 104943
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr12:31123967-31129939 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 12, 13.06 cM, cytoband B1
Mapping Data

3 experiments

SNPs within 2kb

254 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1918813	protein coding gene	Chr12:31123860-31130250 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0019656	protein coding gene	Chr12:29000366-29006194 (+)
A/J	MGP_AJ_G0019623	protein coding gene	Chr12:28193481-28199309 (+)
AKR/J	MGP_AKRJ_G0019594	protein coding gene	Chr12:29084655-29090483 (+)
BALB/cJ	MGP_BALBcJ_G0019600	protein coding gene	Chr12:28420782-28426610 (+)
C3H/HeJ	MGP_C3HHeJ_G0019404	protein coding gene	Chr12:28955112-28960940 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0020047	protein coding gene	Chr12:29904792-29910620 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017672	protein coding gene	Chr12:27487997-27493991 (+)
CAST/EiJ	MGP_CASTEiJ_G0018959	protein coding gene	Chr12:23959329-23965175 (+)
CBA/J	MGP_CBAJ_G0019375	protein coding gene	Chr12:30875282-30881110 (+)
DBA/2J	MGP_DBA2J_G0019489	protein coding gene	Chr12:28026608-28032437 (+)
FVB/NJ	MGP_FVBNJ_G0019480	protein coding gene	Chr12:27818149-27823977 (+)
LP/J	MGP_LPJ_G0019559	protein coding gene	Chr12:29093208-29099036 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019515	protein coding gene	Chr12:30517842-30523670 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020087	protein coding gene	Chr12:28611187-28617015 (+)
PWK/PhJ	MGP_PWKPhJ_G0018726	protein coding gene	Chr12:22752370-22758703 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0018514	protein coding gene	Chr12:23219104-23225099 (+)
WSB/EiJ	MGP_WSBEiJ_G0019009	protein coding gene	Chr12:28850715-28856546 (+)

Human Ortholog

FAM110C, family with sequence similarity 110 member C

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

FAM110C, family with sequence similarity 110 member C
Links

HGNC:33340

NCBI Gene ID: 642273

neXtProt AC: NX_Q1W6H9

UniProt: Q1W6H9
Chr Location

2p25.3; chr2:38814-46870 (-) GRCh38

MGI Vertebrate Homology

Fam110c stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: FAM110C
Gene Tree

Fam110c

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Phenotype Summary

2 phenotype references

All Mutations and Alleles

3
Endonuclease-mediated

3
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

12 strains or lines available

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All GO Annotations

18
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

709
Tissues

2
cDNA Data

24
Literature Summary

3

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase fam110c

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All Sequences

33
RefSeq

2
UniProt

1
CCDS

CCDS25860.1

Ensembl

ENSMUSG00000036136 (Evidence)
NCBI Gene

104943

			Length	Strain/Species	Flank
genomic	104943	NCBI Gene Model \| MGI Sequence Detail	5973	C57BL/6J	± kb
transcript	NM_027828	RefSeq \| MGI Sequence Detail	2684	FVB/N
polypeptide	Q8VE94	UniProt \| EBI \| MGI Sequence Detail	421	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000032660 protein FAM110C

(term hierarchy)
InterPro Domains

IPR025741 Centrosome-associated, FAM110, C-terminal domain

IPR025740 FAM110

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All nucleic 24

cDNA 24

Microarray probesets 4

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MGI:2144949

Summaries

All 30

Developmental Gene Expression 3

Gene Ontology 5

Phenotypes 2
Earliest

J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
Latest

J:355921 Xue L, et al., Global expression profiling reveals genetic programs underlying the developmental divergence between mouse and human embryogenesis. BMC Genomics. 2013 Aug 20;14:568

TSS for Fam110c:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr113098	Chr12:31123883-31123888 (+)	-81 bp
Tssr113099	Chr12:31123897-31123904 (+)	-66 bp
Tssr113100	Chr12:31123946-31123958 (+)	-15 bp
Tssr113101	Chr12:31123961-31123966 (+)	-3 bp
Tssr113102	Chr12:31123969-31124002 (+)	19 bp
Tssr113103	Chr12:31124013-31124029 (+)	54 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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