About   Help   FAQ
Tmem50a Gene Detail
Summary
  • Symbol
    Tmem50a
  • Name
    transmembrane protein 50A
  • Synonyms
    3200001F09Rik, CAM, Smp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919067
    NCBI Gene: 71817
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:134625160-134642307 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 67.14 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    692 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919067
 protein coding gene Chr4:134625160-134642335 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028936
 protein coding gene Chr4:137284906-137304643 (-)
A/J MGP_AJ_G0028895
 protein coding gene Chr4:131505557-131523886 (-)
AKR/J MGP_AKRJ_G0028847
 protein coding gene Chr4:135283669-135311493 (-)
BALB/cJ MGP_BALBcJ_G0028919
 protein coding gene Chr4:132158903-132176098 (-)
C3H/HeJ MGP_C3HHeJ_G0028633
 protein coding gene Chr4:135529319-135550246 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029360
 protein coding gene Chr4:142229820-142254660 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026631
 protein coding gene Chr4:124558927-124574796 (-)
CAST/EiJ MGP_CASTEiJ_G0028065
 protein coding gene Chr4:133658208-133679964 (-)
CBA/J MGP_CBAJ_G0028598
 protein coding gene Chr4:146004385-146031194 (-)
DBA/2J MGP_DBA2J_G0028747
 protein coding gene Chr4:131927023-131943909 (-)
FVB/NJ MGP_FVBNJ_G0028714
 protein coding gene Chr4:130837932-130855961 (-)
LP/J MGP_LPJ_G0028846
 protein coding gene Chr4:137395295-137413884 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028740
 protein coding gene Chr4:150442212-150460452 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029398
 protein coding gene Chr4:135728090-135746013 (-)
PWK/PhJ MGP_PWKPhJ_G0027785
 protein coding gene Chr4:128675493-128696643 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027611
 protein coding gene Chr4:131556074-131574859 (-)
WSB/EiJ MGP_WSBEiJ_G0028143
 protein coding gene Chr4:135900746-135919897 (-)



Homology
more
  • Human Ortholog
    TMEM50A, transmembrane protein 50A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM50A, transmembrane protein 50A
  • Synonyms
    IFNRC, SMP1
  • Links
    NCBI Gene ID: 23585
    neXtProt AC: NX_O95807
    UniProt: O95807

  • Chr Location
    1p36.11; chr1:25338317-25362361 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    137
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71817 NCBI Gene Model | MGI Sequence Detail 17148 C57BL/6J ±  kb
transcript NM_001419210 RefSeq | MGI Sequence Detail 1253 ZRU/MplStud  
polypeptide Q9CXL1 UniProt | EBI | MGI Sequence Detail 157 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 138
    Genomic 1
    cDNA 137

    Microarray probesets 2
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:8214 Schuh R, et al., Molecular cloning of the mouse cell adhesion molecule uvomorulin: cDNA contains a B1-related sequence. Proc Natl Acad Sci U S A. 1986 Mar;83(5):1364-8
  • Latest
    J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory