Tcp11x2 MGI Mouse Gene Detail - MGI:1919091 - t-complex 11 family, X-linked 2

Symbol

Tcp11x2
Name

t-complex 11 family, X-linked 2
Synonyms

1700008I05Rik, Tcp11l3

Feature Type

protein coding gene
IDs

MGI:1919091
NCBI Gene: 71841
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

ChrX:134555447-134594539 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome X, 57.26 cM, cytoband F1
Mapping Data

3 experiments

SNPs within 2kb

952 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1919091	protein coding gene	ChrX:134555447-134594539 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0036087	protein coding gene	ChrX:132994532-133035277 (-)
A/J	MGP_AJ_G0036065	protein coding gene	ChrX:132375482-132424269 (-)
AKR/J	MGP_AKRJ_G0035991	protein coding gene	ChrX:136626190-136666175 (-)
BALB/cJ	MGP_BALBcJ_G0036055	protein coding gene	ChrX:130779926-130827349 (-)
C3H/HeJ	MGP_C3HHeJ_G0035765	protein coding gene	ChrX:132961775-133004530 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0036577	protein coding gene	ChrX:136782661-136823197 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0033406	protein coding gene	ChrX:124427479-124466464 (-)
CAST/EiJ	MGP_CASTEiJ_G0035052	protein coding gene	ChrX:113893535-113938616 (-)
CBA/J	MGP_CBAJ_G0035739	protein coding gene	ChrX:140989910-141033322 (-)
DBA/2J	MGP_DBA2J_G0035895	protein coding gene	ChrX:131727751-131768971 (-)
FVB/NJ	MGP_FVBNJ_G0035832	protein coding gene	ChrX:130917100-130958564 (-)
LP/J	MGP_LPJ_G0035988	protein coding gene	ChrX:133907690-133948106 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0035866	protein coding gene	ChrX:148367142-148408275 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0036613	protein coding gene	ChrX:132333878-132373594 (-)
PWK/PhJ	MGP_PWKPhJ_G0034743	protein coding gene	ChrX:110815604-110860679 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0034575	protein coding gene	ChrX:114531508-114577822 (-)
WSB/EiJ	MGP_WSBEiJ_G0035185	protein coding gene	ChrX:130680968-130722042 (-)

Human Ortholog

TCP11X1, t-complex 11 family, X-linked 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TCP11X1, t-complex 11 family, X-linked 1
Links

HGNC:48369

NCBI Gene ID: 100996631

UniProt: B4DZS4
Chr Location

chrX:102215298-102229532 (+) GRCh38

Human Ortholog

TCP11X2, t-complex 11 family, X-linked 2
Links

HGNC:48335

NCBI Gene ID: 100996648

neXtProt AC: NX_Q5H9J9

UniProt: Q5H9J9
Chr Location

chrX:102456862-102471842 (-) GRCh38

MGI Vertebrate Homology

Tcp11x2 stringent orthology
2 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: TCP11X1, TCP11X2
Gene Tree

Tcp11x2

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References

1 with disease annotations

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
8 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

4
Endonuclease-mediated

2
Targeted

2
Genomic Mutations

1 involving Tcp11x2
Find Mice (IMSR)

5 strains or lines available

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All GO Annotations

4
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

7
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

32
RefSeq

2
UniProt

2
CCDS

CCDS41129.1

Ensembl

ENSMUSG00000058252 (Evidence)
NCBI Gene

71841

			Length	Strain/Species	Flank
genomic	71841	NCBI Gene Model \| MGI Sequence Detail	39093	C57BL/6J	± kb
transcript	NM_027952	RefSeq \| MGI Sequence Detail	1776	C57BL/6
polypeptide	NP_082228	RefSeq \| MGI Sequence Detail	503	C57BL/6

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UniProt

2 Sequences
InterPro Domains

IPR008862 T-complex 11

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All nucleic 7

cDNA 7

Microarray probesets 3

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MGI:2148048

Summaries

All 28

Developmental Gene Expression 1

Diseases 1

Gene Ontology 1

Phenotypes 8
Earliest

J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Tcp11x2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr164174	ChrX:134594532-134594544 (-)	1 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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