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Fbxo30 Gene Detail
Summary
  • Symbol
    Fbxo30
  • Name
    F-box protein 30
  • Synonyms
    1700026A16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919115
    NCBI Gene: 71865
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:11157074-11173796 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 3.66 cM, cytoband A2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    420 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919115
 protein coding gene Chr10:11157009-11181494 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017013
 protein coding gene Chr10:8651212-8668926 (+)
A/J MGP_AJ_G0016991
 protein coding gene Chr10:8261471-8278136 (+)
AKR/J MGP_AKRJ_G0016955
 protein coding gene Chr10:8460263-8476919 (+)
BALB/cJ MGP_BALBcJ_G0016949
 protein coding gene Chr10:8272359-8289024 (+)
C3H/HeJ MGP_C3HHeJ_G0016774
 protein coding gene Chr10:8627440-8645074 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017411
 protein coding gene Chr10:8858547-8877892 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015116
 protein coding gene Chr10:7655655-7672426 (+)
CAST/EiJ MGP_CASTEiJ_G0016356
 protein coding gene Chr10:8495156-8514848 (+)
CBA/J MGP_CBAJ_G0016746
 protein coding gene Chr10:9160048-9176691 (+)
DBA/2J MGP_DBA2J_G0016854
 protein coding gene Chr10:8175575-8192335 (+)
FVB/NJ MGP_FVBNJ_G0016849
 protein coding gene Chr10:8078651-8095142 (+)
LP/J MGP_LPJ_G0016929
 protein coding gene Chr10:8447670-8465978 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016879
 protein coding gene Chr10:9102544-9121281 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017449
 protein coding gene Chr10:8399489-8416981 (+)
PWK/PhJ MGP_PWKPhJ_G0016141
 protein coding gene Chr10:8096754-8114454 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015924
 protein coding gene Chr10:8450066-8467314 (+)
WSB/EiJ MGP_WSBEiJ_G0016418
 protein coding gene Chr10:8423173-8441488 (+)



Homology
more
  • Human Ortholog
    FBXO30, F-box protein 30
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXO30, F-box protein 30
  • Synonyms
    Fbx30
  • Links
    NCBI Gene ID: 84085
    neXtProt AC: NX_Q8TB52
    UniProt: Q8TB52

  • Chr Location
    6q24.3; chr6:145793502-145814795 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    782
  • Tissues
    64
  • cDNA Data
    65
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000047648 Ensembl Gene Model | MGI Sequence Detail 16723 C57BL/6J ±  kb
    transcript ENSMUST00000070300 Ensembl | MGI Sequence Detail 2492 Not Applicable  
    polypeptide ENSMUSP00000068230 Ensembl | MGI Sequence Detail 746 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 65
      cDNA 65

      Microarray probesets 5
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 4
      Gene Ontology 3
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory