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Coq2 Gene Detail
Summary
  • Symbol
    Coq2
  • Name
    coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
  • Synonyms
    2310002F18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919133
    NCBI Gene: 71883
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:100802589-100822154 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 48.50 cM, cytoband E3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    652 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919133
 protein coding gene Chr5:100802589-100823006 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029789
 protein coding gene Chr5:102160476-102180005 (-)
A/J MGP_AJ_G0029755
 protein coding gene Chr5:98351937-98371458 (-)
AKR/J MGP_AKRJ_G0029701
 protein coding gene Chr5:101589949-101612431 (-)
BALB/cJ MGP_BALBcJ_G0029765
 protein coding gene Chr5:99383738-99403267 (-)
C3H/HeJ MGP_C3HHeJ_G0029488
 protein coding gene Chr5:101943884-101963392 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030220
 protein coding gene Chr5:106407780-106427307 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027455
 protein coding gene Chr5:93597121-93616547 (-)
CAST/EiJ MGP_CASTEiJ_G0028899
 protein coding gene Chr5:100601350-100621713 (-)
CBA/J MGP_CBAJ_G0029458
 protein coding gene Chr5:110099406-110118919 (-)
DBA/2J MGP_DBA2J_G0029602
 protein coding gene Chr5:98545717-98565224 (-)
FVB/NJ MGP_FVBNJ_G0029561
 protein coding gene Chr5:97346132-97365644 (-)
LP/J MGP_LPJ_G0029690
 protein coding gene Chr5:102774261-102793784 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029590
 protein coding gene Chr5:115166510-115186039 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030253
 protein coding gene Chr5:101074333-101093851 (-)
PWK/PhJ MGP_PWKPhJ_G0028617
 protein coding gene Chr5:96979770-96999707 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028452
 protein coding gene Chr5:98747056-98767629 (-)
WSB/EiJ MGP_WSBEiJ_G0028977
 protein coding gene Chr5:101405823-101429606 (-)



Homology
more
  • Human Ortholog
    COQ2, coenzyme Q2, polyprenyltransferase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COQ2, coenzyme Q2, polyprenyltransferase
  • Synonyms
    CL640, COQ10D1, MSA1, PHB:PPT
  • Links
    NCBI Gene ID: 27235
    neXtProt AC: NX_Q96H96
    UniProt: Q96H96

  • Chr Location
    4q21.23; chr4:83261536-83285134 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human COQ2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    865
  • Tissues
    136
  • cDNA Data
    60
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 71883 NCBI Gene Model | MGI Sequence Detail 19566 C57BL/6J ±  kb
    transcript NM_027978 RefSeq | MGI Sequence Detail 1712 C57BL/6  
    polypeptide Q66JT7 UniProt | EBI | MGI Sequence Detail 374 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 61
      cDNA 60
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 5
      Gene Ontology 8
      Phenotypes 16
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:347822 Corral-Sarasa J, et al., 4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease. Cell Rep. 2024;:114148
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory