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Tmem123 Gene Detail
Summary
  • Symbol
    Tmem123
  • Name
    transmembrane protein 123
  • Synonyms
    2310075C12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919179
    NCBI Gene: 71929
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:7764078-7794334 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 2.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1069 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919179
 protein coding gene Chr9:7764042-7794334 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034328
 protein coding gene Chr9:4621166-4652791 (+)
A/J MGP_AJ_G0034306
 protein coding gene Chr9:4732718-4763694 (+)
AKR/J MGP_AKRJ_G0034234
 protein coding gene Chr9:4605067-4636796 (+)
BALB/cJ MGP_BALBcJ_G0034300
 protein coding gene Chr9:4478014-4508115 (+)
C3H/HeJ MGP_C3HHeJ_G0034011
 protein coding gene Chr9:4792439-4822598 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034822
 protein coding gene Chr9:4804069-4834064 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031760
 protein coding gene Chr9:3976695-4007338 (+)
CAST/EiJ MGP_CASTEiJ_G0033339
 protein coding gene Chr9:4820164-4851918 (+)
CBA/J MGP_CBAJ_G0033984
 protein coding gene Chr9:4921815-4951916 (+)
DBA/2J MGP_DBA2J_G0034141
 protein coding gene Chr9:4609973-4640829 (+)
FVB/NJ MGP_FVBNJ_G0034086
 protein coding gene Chr9:4382990-4414162 (+)
LP/J MGP_LPJ_G0034227
 protein coding gene Chr9:4684001-4714932 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034130
 protein coding gene Chr9:5668404-5699262 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034841
 protein coding gene Chr9:4600234-4630417 (+)
PWK/PhJ MGP_PWKPhJ_G0033042
 protein coding gene Chr9:4731672-4762615 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032880
 protein coding gene Chr9:4846368-4879033 (+)
WSB/EiJ MGP_WSBEiJ_G0033454
 protein coding gene Chr9:4614885-4650761 (+)



Homology
more
  • Human Ortholog
    TMEM123, transmembrane protein 123
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM123, transmembrane protein 123
  • Synonyms
    KCT3, PORIMIN, PORMIN
  • Links
    NCBI Gene ID: 114908
    neXtProt AC: NX_Q8N131
    UniProt: Q8N131

  • Chr Location
    11q22.2; chr11:102396332-102470384 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Mice homozygous for a knock-out allele exhibit no abnormal phenotype as revealed by limited studies of T cell activation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    209
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71929 NCBI Gene Model | MGI Sequence Detail 30257 C57BL/6J ±  kb
transcript NR_152989 RefSeq | MGI Sequence Detail 2909 C57BL/6  
polypeptide Q91Z22 UniProt | EBI | MGI Sequence Detail 195 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 209
    cDNA 209

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory