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Rpusd4 Gene Detail
Summary
  • Symbol
    Rpusd4
  • Name
    RNA pseudouridylate synthase domain containing 4
  • Synonyms
    2410001E19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919239
    NCBI Gene: 71989
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:35179177-35187253 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 20.15 cM, cytoband A5.3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    340 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919239
 protein coding gene Chr9:35179161-35189027 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034534
 protein coding gene Chr9:33075951-33085751 (+)
A/J MGP_AJ_G0034512
 protein coding gene Chr9:32215943-32225743 (+)
AKR/J MGP_AKRJ_G0034438
 protein coding gene Chr9:32943492-32953237 (+)
BALB/cJ MGP_BALBcJ_G0034503
 protein coding gene Chr9:32132865-32142603 (+)
C3H/HeJ MGP_C3HHeJ_G0034215
 protein coding gene Chr9:33279858-33289705 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035024
 protein coding gene Chr9:34182290-34192199 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031954
 protein coding gene Chr9:30908091-30917769 (+)
CAST/EiJ MGP_CASTEiJ_G0033538
 protein coding gene Chr9:33185762-33195576 (+)
CBA/J MGP_CBAJ_G0034189
 protein coding gene Chr9:35339159-35348958 (+)
DBA/2J MGP_DBA2J_G0034346
 protein coding gene Chr9:32199096-32208898 (+)
FVB/NJ MGP_FVBNJ_G0034289
 protein coding gene Chr9:31613663-31623464 (+)
LP/J MGP_LPJ_G0034432
 protein coding gene Chr9:33328035-33337885 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034333
 protein coding gene Chr9:36910265-36920065 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035044
 protein coding gene Chr9:32898289-32908141 (+)
PWK/PhJ MGP_PWKPhJ_G0033243
 protein coding gene Chr9:32187883-32197768 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033078
 protein coding gene Chr9:33045325-33055243 (+)
WSB/EiJ MGP_WSBEiJ_G0033653
 protein coding gene Chr9:32662992-32672840 (+)



Homology
more
  • Human Ortholog
    RPUSD4, RNA pseudouridine synthase D4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPUSD4, RNA pseudouridine synthase D4
  • Links
    NCBI Gene ID: 84881
    neXtProt AC: NX_Q96CM3
    UniProt: Q96CM3

  • Chr Location
    11q24.2; chr11:126202096-126211692 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    733
  • Tissues
    26
  • cDNA Data
    47
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71989 NCBI Gene Model | MGI Sequence Detail 8077 C57BL/6J ±  kb
transcript NM_028040 RefSeq | MGI Sequence Detail 1827 Not Specified  
polypeptide Q9CWX4 UniProt | EBI | MGI Sequence Detail 377 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000030305 pseudouridylate synthase RPUSD4, mitochondrial
    (term hierarchy)
  • EC
    5.4.99.-
  • InterPro Domains
    IPR020103 Pseudouridine synthase, catalytic domain superfamily
    IPR006224 Pseudouridine synthase, RluA-like, conserved site
    IPR006145 Pseudouridine synthase, RsuA/RluA-like
    IPR050188 RluA Pseudouridine Synthase
  • GlyGen
    Q9CWX4 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 47
    cDNA 47

    Microarray probesets 3
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory