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Urgcp Gene Detail
Summary
  • Symbol
    Urgcp
  • Name
    upregulator of cell proliferation
  • Synonyms
    2010005J08Rik, mKIAA1507
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919296
    NCBI Gene: 72046
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:5663417-5712376 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 3.87 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1224 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919296
 protein coding gene Chr11:5663417-5712376 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018005
 protein coding gene Chr11:2780484-2816571 (-)
A/J MGP_AJ_G0017978
 protein coding gene Chr11:2677594-2709767 (-)
AKR/J MGP_AKRJ_G0017942
 protein coding gene Chr11:2823351-2849101 (-)
BALB/cJ MGP_BALBcJ_G0017946
 protein coding gene Chr11:2670236-2700069 (-)
C3H/HeJ MGP_C3HHeJ_G0017759
 protein coding gene Chr11:2697038-2723585 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018398
 protein coding gene Chr11:2860405-2890554 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016056
 protein coding gene Chr11:2567999-2594683 (-)
CAST/EiJ MGP_CASTEiJ_G0017321
 protein coding gene Chr11:2650518-2680299 (-)
CBA/J MGP_CBAJ_G0017734
 protein coding gene Chr11:3205233-3236044 (-)
DBA/2J MGP_DBA2J_G0017844
 protein coding gene Chr11:2580593-2614616 (-)
FVB/NJ MGP_FVBNJ_G0017836
 protein coding gene Chr11:2618620-2644417 (-)
LP/J MGP_LPJ_G0017915
 protein coding gene Chr11:2869045-2899042 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017862
 protein coding gene Chr11:2823325-2859785 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018438
 protein coding gene Chr11:2823233-2855980 (-)
PWK/PhJ MGP_PWKPhJ_G0017101
 protein coding gene Chr11:2608262-2660105 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016898
 protein coding gene Chr11:2788889-2815416 (-)
WSB/EiJ MGP_WSBEiJ_G0017375
 protein coding gene Chr11:2670405-2698631 (-)



Homology
more
  • Human Ortholog
    URGCP, upregulator of cell proliferation
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    URGCP, upregulator of cell proliferation
  • Synonyms
    URG4
  • Links
    NCBI Gene ID: 55665
    neXtProt AC: NX_Q8TCY9
    UniProt: Q8TCY9

  • Chr Location
    7p13; chr7:43875894-43926726 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    76
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72046 NCBI Gene Model | MGI Sequence Detail 48960 C57BL/6J ±  kb
transcript NM_001361588 RefSeq | MGI Sequence Detail 5778 C57BL/6  
polypeptide Q5NCI0 UniProt | EBI | MGI Sequence Detail 926 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000017132 up-regulator of cell proliferation
    (term hierarchy)
  • InterPro Domains
    IPR006073 GTP binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR030383 Very large inducible GTPASE (VLIG)-type guanine nucleotide-binding (G) domain
Molecular
Reagents
less
  • All nucleic 77
    cDNA 77

    Microarray probesets 5
Other
Accession IDs
less
MGI:2144491
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory