Slc38a10 MGI Mouse Gene Detail - MGI:1919305 - solute carrier family 38, member 10

Symbol

Slc38a10
Name

solute carrier family 38, member 10
Synonyms

1810073N04Rik

Feature Type

protein coding gene
IDs

MGI:1919305
NCBI Gene: 72055
Alliance

gene page
Transcription Start Sites

8 TSS

Sequence Map

Chr11:119994786-120042172 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 83.96 cM
Mapping Data

2 experiments

SNPs within 2kb

1256 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1919305	protein coding gene	Chr11:119994777-120042177 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0019492	protein coding gene	Chr11:124542868-124591938 (-)
A/J	MGP_AJ_G0019460	protein coding gene	Chr11:119007344-119054698 (-)
AKR/J	MGP_AKRJ_G0019430	protein coding gene	Chr11:122587548-122635321 (-)
BALB/cJ	MGP_BALBcJ_G0019435	protein coding gene	Chr11:119363927-119411282 (-)
C3H/HeJ	MGP_C3HHeJ_G0019241	protein coding gene	Chr11:122908741-122956077 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0019884	protein coding gene	Chr11:128316637-128364889 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017509	protein coding gene	Chr11:116013473-116061269 (-)
CAST/EiJ	MGP_CASTEiJ_G0018795	protein coding gene	Chr11:124393041-124442825 (-)
CBA/J	MGP_CBAJ_G0019212	protein coding gene	Chr11:133326508-133377462 (-)
DBA/2J	MGP_DBA2J_G0019324	protein coding gene	Chr11:118373351-118421816 (-)
FVB/NJ	MGP_FVBNJ_G0019316	protein coding gene	Chr11:118066625-118113820 (-)
LP/J	MGP_LPJ_G0019396	protein coding gene	Chr11:124850720-124899950 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019349	protein coding gene	Chr11:132189501-132241911 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019923	protein coding gene	Chr11:123269478-123320304 (-)
PWK/PhJ	MGP_PWKPhJ_G0018561	protein coding gene	Chr11:119801441-119849670 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0018353	protein coding gene	Chr11:123039010-123089931 (-)
WSB/EiJ	MGP_WSBEiJ_G0018847	protein coding gene	Chr11:123268117-123316447 (-)

Human Ortholog

SLC38A10, solute carrier family 38 member 10

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SLC38A10, solute carrier family 38 member 10
Synonyms

PP1744, SNAT10
Links

HGNC:28237

NCBI Gene ID: 124565

neXtProt AC: NX_Q9HBR0

UniProt: Q9HBR0
Chr Location

17q25.3; chr17:81244811-81295547 (-) GRCh38

MGI Vertebrate Homology

Slc38a10 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: SLC38A10
Gene Tree

Slc38a10

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Phenotype Summary

32 phenotypes from 2 alleles in 4 genetic backgrounds
19 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

9
Endonuclease-mediated

1
Gene trapped

3
Targeted

5
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

34 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Homozygous null mice exhibit a fragile skeleton, reduced adiposity, lean body mass, body weight/length, long bone length and bone mineral density, increased creatinine levels, reduced amylase and serum albumin levels, increased energy efficiency and oxygen consumption, and altered liver physiology.

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All GO Annotations

8
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

944
Tissues

100
cDNA Data

199
Literature Summary

4

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase slc38a10

ZFIN slc38a10

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All Sequences

157
RefSeq

52
UniProt

5
CCDS

CCDS25728.1, CCDS49000.1, CCDS49001.1, CCDS49002.1

Ensembl

ENSMUSG00000061306 (Evidence)
NCBI Gene

72055

			Length	Strain/Species	Flank
genomic	ENSMUSG00000061306	Ensembl Gene Model \| MGI Sequence Detail	47387	C57BL/6J	± kb
transcript	ENSMUST00000103018	Ensembl \| MGI Sequence Detail	4578	Not Applicable
polypeptide	ENSMUSP00000099307	Ensembl \| MGI Sequence Detail	1090	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000029740 solute carrier family 38 member 10

(term hierarchy)
InterPro Domains

IPR013057 Amino acid transporter, transmembrane domain

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All nucleic 199

cDNA 199

Microarray probesets 10

Summaries

All 47

Developmental Gene Expression 4

Gene Ontology 6

Phenotypes 19
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Slc38a10:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr112273	Chr11:120042020-120042180 (-)	72 bp
Tssr112272	Chr11:120033716-120033717 (-)	8,455 bp
Tssr112271	Chr11:120030321-120030322 (-)	11,850 bp
Tssr112270	Chr11:120030275-120030277 (-)	11,896 bp
Tssr112269	Chr11:120030262-120030274 (-)	11,904 bp
Tssr112268	Chr11:120030253-120030258 (-)	11,916 bp
Tssr112267	Chr11:120030233-120030248 (-)	11,931 bp
Tssr112266	Chr11:120027524-120027533 (-)	14,643 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24