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Pygo1 Gene Detail
Summary
  • Symbol
    Pygo1
  • Name
    pygopus 1
  • Synonyms
    2600014C22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919385
    NCBI Gene: 72135
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:72832927-72859463 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 40.08 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    759 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919385
 protein coding gene Chr9:72832927-72859868 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035019
 protein coding gene Chr9:73126737-73154383 (+)
A/J MGP_AJ_G0035000
 protein coding gene Chr9:70570514-70597165 (+)
AKR/J MGP_AKRJ_G0034929
 protein coding gene Chr9:72263873-72290403 (+)
BALB/cJ MGP_BALBcJ_G0034992
 protein coding gene Chr9:70277778-70304306 (+)
C3H/HeJ MGP_C3HHeJ_G0034701
 protein coding gene Chr9:72754677-72781200 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035511
 protein coding gene Chr9:75051984-75078520 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032422
 protein coding gene Chr9:70045012-70072298 (+)
CAST/EiJ MGP_CASTEiJ_G0034023
 protein coding gene Chr9:73089706-73118686 (+)
CBA/J MGP_CBAJ_G0034674
 protein coding gene Chr9:77671634-77698168 (+)
DBA/2J MGP_DBA2J_G0034833
 protein coding gene Chr9:70287594-70314618 (+)
FVB/NJ MGP_FVBNJ_G0034775
 protein coding gene Chr9:69596467-69622938 (+)
LP/J MGP_LPJ_G0034914
 protein coding gene Chr9:73353893-73381194 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034816
 protein coding gene Chr9:78750179-78776712 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035533
 protein coding gene Chr9:72415463-72441995 (+)
PWK/PhJ MGP_PWKPhJ_G0033727
 protein coding gene Chr9:70565268-70592840 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033560
 protein coding gene Chr9:72705506-72733129 (+)
WSB/EiJ MGP_WSBEiJ_G0034135
 protein coding gene Chr9:72349552-72377416 (+)



Homology
more
  • Human Ortholog
    PYGO1, pygopus family PHD finger 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PYGO1, pygopus family PHD finger 1
  • Links
    NCBI Gene ID: 26108
    neXtProt AC: NX_Q9Y3Y4
    UniProt: Q9Y3Y4

  • Chr Location
    15q21.3; chr15:55538884-55588971 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    16 phenotypes from multigenic genotypes
    1 images
    14 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Targeted
    6
  • Genomic Mutations
    1 involving Pygo1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    21 strains or lines available
Homozygous null mice are viable and show no obvious phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    865
  • Tissues
    149
  • cDNA Data
    20
  • Literature Summary
    12
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034910 Ensembl Gene Model | MGI Sequence Detail 26537 C57BL/6J ±  kb
transcript ENSMUST00000038489 Ensembl | MGI Sequence Detail 7916 Not Applicable  
polypeptide ENSMUSP00000044368 Ensembl | MGI Sequence Detail 417 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 20
    Primer pair 4

    Microarray probesets 2
References
more
  • Summaries
    All 51
    Developmental Gene Expression 12
    Gene Ontology 9
    Phenotypes 14
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory