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Thumpd2 Gene Detail
Summary
  • Symbol
    Thumpd2
  • Name
    THUMP domain containing 2
  • Synonyms
    2810025A12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919417
    NCBI Gene: 72167
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:81333761-81372511 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 51.04 cM, cytoband E3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1390 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919417
 protein coding gene Chr17:81331676-81372542 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024068
 protein coding gene Chr17:84002021-84041644 (-)
A/J MGP_AJ_G0024026
 protein coding gene Chr17:81410763-81449366 (-)
AKR/J MGP_AKRJ_G0023995
 protein coding gene Chr17:82697640-82736346 (-)
BALB/cJ MGP_BALBcJ_G0024028
 protein coding gene Chr17:81271492-81310080 (-)
C3H/HeJ MGP_C3HHeJ_G0023792
 protein coding gene Chr17:83546372-83586747 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024472
 protein coding gene Chr17:87028293-87067417 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021912
 protein coding gene Chr17:76752749-76788969 (-)
CAST/EiJ MGP_CASTEiJ_G0023271
 protein coding gene Chr17:84265799-84307992 (-)
CBA/J MGP_CBAJ_G0023766
 protein coding gene Chr17:90665118-90704915 (-)
DBA/2J MGP_DBA2J_G0023895
 protein coding gene Chr17:79890004-79928755 (-)
FVB/NJ MGP_FVBNJ_G0023861
 protein coding gene Chr17:79383540-79422683 (-)
LP/J MGP_LPJ_G0023978
 protein coding gene Chr17:84827298-84867047 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023889
 protein coding gene Chr17:90682797-90723800 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024517
 protein coding gene Chr17:83175473-83214741 (-)
PWK/PhJ MGP_PWKPhJ_G0023017
 protein coding gene Chr17:79463935-79503078 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022828
 protein coding gene Chr17:79961784-80002412 (-)
WSB/EiJ MGP_WSBEiJ_G0023339
 protein coding gene Chr17:84003456-84044670 (-)



Homology
more
  • Human Ortholog
    THUMPD2, THUMP domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    THUMPD2, THUMP domain containing 2
  • Synonyms
    C2orf8
  • Links
    NCBI Gene ID: 80745
    neXtProt AC: NX_Q9BTF0
    UniProt: Q9BTF0

  • Chr Location
    2p22.1; chr2:39736060-39779276 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    17
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024246 Ensembl Gene Model | MGI Sequence Detail 38751 C57BL/6J ±  kb
transcript ENSMUST00000025093 Ensembl | MGI Sequence Detail 1833 Not Applicable  
polypeptide ENSMUSP00000025093 Ensembl | MGI Sequence Detail 528 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000031221 THUMP domain-containing protein 2
    (term hierarchy)
  • InterPro Domains
    IPR000241 Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
    IPR004114 THUMP domain
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory