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Fbxl2 Gene Detail
Summary
  • Symbol
    Fbxl2
  • Name
    F-box and leucine-rich repeat protein 2
  • Synonyms
    2810423A21Rik, Fbl3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919429
    NCBI Gene: 72179
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:113787625-113855871 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 64.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2011 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919429
 protein coding gene Chr9:113787625-113875259 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035382
 protein coding gene Chr9:116354568-116443185 (-)
A/J MGP_AJ_G0035363
 protein coding gene Chr9:112023755-112112701 (-)
AKR/J MGP_AKRJ_G0035294
 protein coding gene Chr9:114877244-114966566 (-)
BALB/cJ MGP_BALBcJ_G0035358
 protein coding gene Chr9:111846203-111927743 (-)
C3H/HeJ MGP_C3HHeJ_G0035066
 protein coding gene Chr9:115396811-115487799 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035879
 protein coding gene Chr9:119510447-119597554 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032766
 protein coding gene Chr9:109173094-109237743 (-)
CAST/EiJ MGP_CASTEiJ_G0034372
 protein coding gene Chr9:115252157-115332562 (-)
CBA/J MGP_CBAJ_G0035033
 protein coding gene Chr9:123913303-124006136 (-)
DBA/2J MGP_DBA2J_G0035191
 protein coding gene Chr9:111492168-111573081 (-)
FVB/NJ MGP_FVBNJ_G0035138
 protein coding gene Chr9:110310912-110398087 (-)
LP/J MGP_LPJ_G0035271
 protein coding gene Chr9:116646654-116731146 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035179
 protein coding gene Chr9:125160870-125242209 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035900
 protein coding gene Chr9:115279168-115360792 (-)
PWK/PhJ MGP_PWKPhJ_G0034077
 protein coding gene Chr9:111785239-111867010 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033912
 protein coding gene Chr9:115333199-115418558 (-)
WSB/EiJ MGP_WSBEiJ_G0034492
 protein coding gene Chr9:115123653-115209199 (-)



Homology
more
  • Human Ortholog
    FBXL2, F-box and leucine rich repeat protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXL2, F-box and leucine rich repeat protein 2
  • Synonyms
    FBL2, FBL3
  • Links
    NCBI Gene ID: 25827
    neXtProt AC: NX_Q9UKC9
    UniProt: Q9UKC9

  • Chr Location
    3p22.3; chr3:33277025-33422698 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    734
  • Tissues
    3
  • cDNA Data
    13
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72179 NCBI Gene Model | MGI Sequence Detail 68247 C57BL/6J ±  kb
transcript NM_178624 RefSeq | MGI Sequence Detail 3465 C57BL/6  
polypeptide Q8BH16 UniProt | EBI | MGI Sequence Detail 423 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:196439 Chen BB, et al., A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation. Nat Immunol. 2013 May;14(5):470-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory