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Wdr89 Gene Detail
Summary
  • Symbol
    Wdr89
  • Name
    WD repeat domain 89
  • Synonyms
    2600001A11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919588
    NCBI Gene: 72338
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:75677370-75716311 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 32.89 cM, cytoband D1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1179 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919588
 protein coding gene Chr12:75677368-75716311 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019849
 protein coding gene Chr12:75663233-75709166 (-)
A/J MGP_AJ_G0019807
 protein coding gene Chr12:72828066-72868757 (-)
AKR/J MGP_AKRJ_G0019782
 protein coding gene Chr12:75024999-75071026 (-)
BALB/cJ MGP_BALBcJ_G0019786
 protein coding gene Chr12:73290286-73329739 (-)
C3H/HeJ MGP_C3HHeJ_G0019592
 protein coding gene Chr12:75486720-75527893 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020238
 protein coding gene Chr12:78029848-78069518 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017856
 protein coding gene Chr12:70166753-70204802 (-)
CAST/EiJ MGP_CASTEiJ_G0019143
 protein coding gene Chr12:70278513-70322900 (-)
CBA/J MGP_CBAJ_G0019562
 protein coding gene Chr12:81021242-81067273 (-)
DBA/2J MGP_DBA2J_G0019678
 protein coding gene Chr12:72687390-72726902 (-)
FVB/NJ MGP_FVBNJ_G0019665
 protein coding gene Chr12:71515631-71553934 (-)
LP/J MGP_LPJ_G0019750
 protein coding gene Chr12:75671221-75713515 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019704
 protein coding gene Chr12:84082024-84122487 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020274
 protein coding gene Chr12:74502692-74543452 (-)
PWK/PhJ MGP_PWKPhJ_G0018909
 protein coding gene Chr12:67034948-67074907 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018703
 protein coding gene Chr12:68991665-69033705 (-)
WSB/EiJ MGP_WSBEiJ_G0019195
 protein coding gene Chr12:75102115-75142643 (-)



Homology
more
  • Human Ortholog
    WDR89, WD repeat domain 89
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR89, WD repeat domain 89
  • Synonyms
    C14orf150, MSTP050
  • Links
    NCBI Gene ID: 112840
    neXtProt AC: NX_Q96FK6
    UniProt: Q96FK6

  • Chr Location
    14q23.2; chr14:63597039-63641871 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced allele exhibit normal blood lymphocyte populations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    163
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000045690 Ensembl Gene Model | MGI Sequence Detail 38942 C57BL/6J ±  kb
    transcript ENSMUST00000062370 Ensembl | MGI Sequence Detail 2979 Not Applicable  
    polypeptide ENSMUSP00000050532 Ensembl | MGI Sequence Detail 386 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 166
      cDNA 166

      Microarray probesets 1
    References
    more
    • Summaries
      All 35
      Gene Ontology 1
      Phenotypes 15
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory