About   Help   FAQ
Wdr43 Gene Detail
Summary
  • Symbol
    Wdr43
  • Name
    WD repeat domain 43
  • Synonyms
    2610318G08Rik, mKIAA0007
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919765
    NCBI Gene: 72515
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:71923175-71966026 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 41.87 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1346 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919765
 protein coding gene Chr17:71922890-71966026 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024011
 protein coding gene Chr17:74081153-74127516 (+)
A/J MGP_AJ_G0023969
 protein coding gene Chr17:71835959-71879751 (+)
AKR/J MGP_AKRJ_G0023938
 protein coding gene Chr17:72803193-72848524 (+)
BALB/cJ MGP_BALBcJ_G0023970
 protein coding gene Chr17:71769702-71812423 (+)
C3H/HeJ MGP_C3HHeJ_G0023734
 protein coding gene Chr17:73763539-73809762 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024416
 protein coding gene Chr17:76790171-76832653 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021861
 protein coding gene Chr17:67581943-67624427 (+)
CAST/EiJ MGP_CASTEiJ_G0023215
 protein coding gene Chr17:74206503-74253123 (+)
CBA/J MGP_CBAJ_G0023709
 protein coding gene Chr17:79986078-80035226 (+)
DBA/2J MGP_DBA2J_G0023838
 protein coding gene Chr17:70493807-70536865 (+)
FVB/NJ MGP_FVBNJ_G0023804
 protein coding gene Chr17:69964697-70010325 (+)
LP/J MGP_LPJ_G0023920
 protein coding gene Chr17:74814791-74860814 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023832
 protein coding gene Chr17:79841828-79887411 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024460
 protein coding gene Chr17:73332410-73379906 (+)
PWK/PhJ MGP_PWKPhJ_G0022961
 protein coding gene Chr17:69803693-69846610 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022772
 protein coding gene Chr17:70038950-70084798 (+)
WSB/EiJ MGP_WSBEiJ_G0023282
 protein coding gene Chr17:74165290-74212069 (+)



Homology
more
  • Human Ortholog
    WDR43, WD repeat domain 43
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR43, WD repeat domain 43
  • Synonyms
    NET12, UTP5
  • Links
    NCBI Gene ID: 23160
    neXtProt AC: NX_Q15061
    UniProt: Q15061

  • Chr Location
    2p23.2; chr2:28894667-28948219 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    777
  • Tissues
    20
  • cDNA Data
    149
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72515 NCBI Gene Model | MGI Sequence Detail 42852 C57BL/6J ±  kb
transcript NM_175639 RefSeq | MGI Sequence Detail 3450 C57BL/6  
polypeptide Q6ZQL4 UniProt | EBI | MGI Sequence Detail 677 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000030959 WD repeat-containing protein 43
    (term hierarchy)
  • InterPro Domains
    IPR007148 Small-subunit processome, Utp12
    IPR052414 U3 small nucleolar RNA-associated WD repeat-containing protein
    IPR001680 WD40 repeat
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
  • GlyGen
    Q6ZQL4 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 151
    cDNA 149
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:2146986, MGI:2147012
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:342644 Tscherner AK, et al., Relationship of quantitative reverse transcription polymerase chain reaction (RT-PCR) to RNA Sequencing (RNAseq) transcriptome identifies mouse preimplantation embryo reference genes. Biol Reprod. 2023 Nov 15;109(5):601-617
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory