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Mvb12b Gene Detail
Summary
  • Symbol
    Mvb12b
  • Name
    multivesicular body subunit 12B
  • Synonyms
    2610200O14Rik, 2610528K11Rik, Fam125b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919793
    NCBI Gene: 72543
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:33619965-33777958 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 22.51 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3980 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919793
 protein coding gene Chr2:33619965-33777958 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025636
 protein coding gene Chr2:32271758-32437121 (-)
A/J MGP_AJ_G0025613
 protein coding gene Chr2:30901423-31065250 (-)
AKR/J MGP_AKRJ_G0025583
 protein coding gene Chr2:32008167-32177275 (-)
BALB/cJ MGP_BALBcJ_G0025610
 protein coding gene Chr2:31017833-31177140 (-)
C3H/HeJ MGP_C3HHeJ_G0025370
 protein coding gene Chr2:31891386-32057120 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026054
 protein coding gene Chr2:33224660-33400562 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023463
 protein coding gene Chr2:29629307-29788173 (-)
CAST/EiJ MGP_CASTEiJ_G0024832
 protein coding gene Chr2:31863954-32028964 (-)
CBA/J MGP_CBAJ_G0025348
 protein coding gene Chr2:34511183-34682904 (-)
DBA/2J MGP_DBA2J_G0025481
 protein coding gene Chr2:30682735-30842918 (-)
FVB/NJ MGP_FVBNJ_G0025443
 protein coding gene Chr2:30566717-30728111 (-)
LP/J MGP_LPJ_G0025567
 protein coding gene Chr2:32178386-32343161 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025474
 protein coding gene Chr2:34063206-34225734 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026112
 protein coding gene Chr2:31886411-32044421 (-)
PWK/PhJ MGP_PWKPhJ_G0024580
 protein coding gene Chr2:30587712-30749281 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024380
 protein coding gene Chr2:32058675-32225714 (-)
WSB/EiJ MGP_WSBEiJ_G0024901
 protein coding gene Chr2:32063194-32226523 (-)



Homology
more
  • Human Ortholog
    MVB12B, multivesicular body subunit 12B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MVB12B, multivesicular body subunit 12B
  • Synonyms
    C9orf28, FAM125B
  • Links
    NCBI Gene ID: 89853
    neXtProt AC: NX_Q9H7P6
    UniProt: Q9H7P6

  • Chr Location
    9q33.3; chr9:126326829-126507041 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    4
  • cDNA Data
    117
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72543 NCBI Gene Model | MGI Sequence Detail 157994 C57BL/6J ±  kb
transcript NM_175184 RefSeq | MGI Sequence Detail 4995 C57BL/6  
polypeptide Q6KAU4 UniProt | EBI | MGI Sequence Detail 317 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 120
    Genomic 2
    cDNA 117
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1917692, MGI:2138931
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory