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Cdc42se2 Gene Detail
Summary
  • Symbol
    Cdc42se2
  • Name
    CDC42 small effector 2
  • Synonyms
    2810404F18Rik, SPEC2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919979
    NCBI Gene: 72729
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:54608282-54678501 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 32.13 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1496 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919979
 protein coding gene Chr11:54608241-54678549 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018318
 protein coding gene Chr11:54197021-54275132 (-)
A/J MGP_AJ_G0018287
 protein coding gene Chr11:52178358-52250491 (-)
AKR/J MGP_AKRJ_G0018256
 protein coding gene Chr11:53887654-53960456 (-)
BALB/cJ MGP_BALBcJ_G0018258
 protein coding gene Chr11:52522556-52597304 (-)
C3H/HeJ MGP_C3HHeJ_G0018069
 protein coding gene Chr11:53820203-53899449 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018710
 protein coding gene Chr11:55857939-55932599 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016360
 protein coding gene Chr11:49624897-49693043 (-)
CAST/EiJ MGP_CASTEiJ_G0017634
 protein coding gene Chr11:53869573-53941245 (-)
CBA/J MGP_CBAJ_G0018044
 protein coding gene Chr11:58499965-58574562 (-)
DBA/2J MGP_DBA2J_G0018153
 protein coding gene Chr11:51888084-51960164 (-)
FVB/NJ MGP_FVBNJ_G0018145
 protein coding gene Chr11:51541482-51611700 (-)
LP/J MGP_LPJ_G0018228
 protein coding gene Chr11:54649832-54725782 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018171
 protein coding gene Chr11:59717924-59793239 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018752
 protein coding gene Chr11:53898534-53975192 (-)
PWK/PhJ MGP_PWKPhJ_G0017407
 protein coding gene Chr11:52430943-52502837 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017202
 protein coding gene Chr11:53681621-53764642 (-)
WSB/EiJ MGP_WSBEiJ_G0017682
 protein coding gene Chr11:53535135-53612970 (-)



Homology
more
  • Human Ortholog
    CDC42SE2, CDC42 small effector 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDC42SE2, CDC42 small effector 2
  • Synonyms
    SPEC2
  • Links
    NCBI Gene ID: 56990
    neXtProt AC: NX_Q9NRR3
    UniProt: Q9NRR3

  • Chr Location
    5q31.1; chr5:131210052-131398447 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    79
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    75
  • Targeted
    2
  • Genomic Mutations
    1 involving Cdc42se2
  • Find Mice (IMSR)
    48 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    15
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000052298 Ensembl Gene Model | MGI Sequence Detail 70220 C57BL/6J ±  kb
transcript ENSMUST00000064104 Ensembl | MGI Sequence Detail 3069 Not Applicable  
polypeptide ENSMUSP00000070725 Ensembl | MGI Sequence Detail 84 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 3
Other
Accession IDs
less
MGI:2143986, MGI:2144021
References
more
  • Summaries
    All 40
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory