About   Help   FAQ
Anln Gene Detail
Summary
  • Symbol
    Anln
  • Name
    anillin, actin binding protein
  • Synonyms
    1110037A17Rik, 2900037I21Rik, Scraps
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920174
    NCBI Gene: 68743
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr9:22243308-22300484 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 8.93 cM, cytoband A4
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1380 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920174
 protein coding gene Chr9:22243305-22302132 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034485
 protein coding gene Chr9:19634790-19696666 (-)
A/J MGP_AJ_G0034463
 protein coding gene Chr9:19242535-19301831 (-)
AKR/J MGP_AKRJ_G0034389
 protein coding gene Chr9:19631015-19690334 (-)
BALB/cJ MGP_BALBcJ_G0034454
 protein coding gene Chr9:19122687-19182131 (-)
C3H/HeJ MGP_C3HHeJ_G0034166
 protein coding gene Chr9:19946689-20009417 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034975
 protein coding gene Chr9:20415182-20491275 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031905
 protein coding gene Chr9:18351566-18412100 (-)
CAST/EiJ MGP_CASTEiJ_G0033489
 protein coding gene Chr9:19789440-19852725 (-)
CBA/J MGP_CBAJ_G0034139
 protein coding gene Chr9:21208081-21274541 (-)
DBA/2J MGP_DBA2J_G0034297
 protein coding gene Chr9:19215160-19272188 (-)
FVB/NJ MGP_FVBNJ_G0034240
 protein coding gene Chr9:18771662-18832419 (-)
LP/J MGP_LPJ_G0034383
 protein coding gene Chr9:19823784-19884858 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034284
 protein coding gene Chr9:22774962-22842845 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034995
 protein coding gene Chr9:19588455-19651427 (-)
PWK/PhJ MGP_PWKPhJ_G0033194
 protein coding gene Chr9:19230694-19290878 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033028
 protein coding gene Chr9:19637278-19703363 (-)
WSB/EiJ MGP_WSBEiJ_G0033604
 protein coding gene Chr9:19327693-19392530 (-)



Homology
more
  • Human Ortholog
    ANLN, anillin, actin binding protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANLN, anillin, actin binding protein
  • Synonyms
    FSGS8, scra, Scraps
  • Links
    NCBI Gene ID: 54443
    neXtProt AC: NX_Q9NQW6
    UniProt: Q9NQW6

  • Chr Location
    7p14.2; chr7:36389821-36453791 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ANLN associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 2 alleles in 3 genetic backgrounds
    1 images
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele show delayed embryonic development with poorly organized epithelia and complete embryonic lethality by E9.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    759
  • Tissues
    14
  • cDNA Data
    20
  • Literature Summary
    13
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036777 Ensembl Gene Model | MGI Sequence Detail 57177 C57BL/6J ±  kb
    transcript ENSMUST00000040912 Ensembl | MGI Sequence Detail 4605 Not Applicable  
    polypeptide ENSMUSP00000045873 Ensembl | MGI Sequence Detail 1121 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 23
      cDNA 20
      Primer pair 2
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1915993, MGI:2143393
    References
    more
    • Summaries
      All 65
      Developmental Gene Expression 13
      Gene Ontology 7
      Phenotypes 15
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:354248 Vial Y, et al., Mcph1, mutated in primary microcephaly, is also crucial for erythropoiesis. EMBO Rep. 2024 May;25(5):2418-2440
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory