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Clec4a3 Gene Detail
Summary
  • Symbol
    Clec4a3
  • Name
    C-type lectin domain family 4, member a3
  • Synonyms
    3110037K17Rik, mDcir3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920399
    NCBI Gene: 73149
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:122929474-122946834 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 58.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    393 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920399
 protein coding gene Chr6:122929474-122946837 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031237
 protein coding gene Chr6:126077100-126089190 (+)
A/J MGP_AJ_G0031206
 protein coding gene Chr6:121296186-121310392 (+)
AKR/J MGP_AKRJ_G0031136
 protein coding gene Chr6:124656022-124672680 (+)
BALB/cJ MGP_BALBcJ_G0031216
 protein coding gene Chr6:121011352-121022281 (+)
C3H/HeJ MGP_C3HHeJ_G0030935
 protein coding gene Chr6:124621075-124638021 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031675
 protein coding gene Chr6:129412323-129426231 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028831
 protein coding gene Chr6:117900213-117910416 (+)
CAST/EiJ MGP_CASTEiJ_G0030324
 protein coding gene Chr6:124886527-124896533 (+)
CBA/J MGP_CBAJ_G0030898
 protein coding gene Chr6:134445626-134468756 (+)
DBA/2J MGP_DBA2J_G0031054
 protein coding gene Chr6:120234510-120247968 (+)
FVB/NJ MGP_FVBNJ_G0031007
 protein coding gene Chr6:119168284-119186071 (+)
LP/J MGP_LPJ_G0031135
 protein coding gene Chr6:126267926-126279282 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031042
 protein coding gene Chr6:138409665-138424278 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031705
 protein coding gene Chr6:124545170-124562323 (+)
PWK/PhJ MGP_PWKPhJ_G0030038
 protein coding gene Chr6:119067266-119078597 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029866
 protein coding gene Chr6:122691523-122701696 (+)
WSB/EiJ MGP_WSBEiJ_G0030406
 protein coding gene Chr6:124856697-124866760 (+)



Homology
more
  • Human Ortholog
    CLEC4A, C-type lectin domain family 4 member A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLEC4A, C-type lectin domain family 4 member A
  • Synonyms
    CD367, CLECSF6, DCIR, DDB27, HDCGC13P, hDCIR, LLIR
  • Links
    NCBI Gene ID: 50856
    neXtProt AC: NX_Q9UMR7
    UniProt: Q9UMR7

  • Chr Location
    12p13.31; chr12:8102907-8138607 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    15
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043832 Ensembl Gene Model | MGI Sequence Detail 17361 C57BL/6J ±  kb
transcript ENSMUST00000117173 Ensembl | MGI Sequence Detail 1165 Not Applicable  
polypeptide ENSMUSP00000112716 Ensembl | MGI Sequence Detail 237 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001969 Aspartic peptidase, active site
    IPR033989 CD209-like, C-type lectin-like domain
    IPR050111 C-type lectin and snaclec domain-containing protein
    IPR018378 C-type lectin, conserved site
    IPR016187 C-type lectin fold
    IPR001304 C-type lectin-like
    IPR016186 C-type lectin-like/link domain superfamily
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 2
References
more
  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory