About   Help   FAQ
Rassf6 Gene Detail
Summary
  • Symbol
    Rassf6
  • Name
    Ras association (RalGDS/AF-6) domain family member 6
  • Synonyms
    1600016B17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920496
    NCBI Gene: 73246
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:90750935-90788516 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 44.78 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1407 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920496
 protein coding gene Chr5:90750933-90788594 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029725
 protein coding gene Chr5:91682060-91725157 (-)
A/J MGP_AJ_G0029691
 protein coding gene Chr5:88065144-88102945 (-)
AKR/J MGP_AKRJ_G0029637
 protein coding gene Chr5:90929534-90966905 (-)
BALB/cJ MGP_BALBcJ_G0029701
 protein coding gene Chr5:88952796-88997055 (-)
C3H/HeJ MGP_C3HHeJ_G0029424
 protein coding gene Chr5:91338127-91375562 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030155
 protein coding gene Chr5:95347655-95387478 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027391
 protein coding gene Chr5:83773806-83811471 (-)
CAST/EiJ MGP_CASTEiJ_G0028834
 protein coding gene Chr5:90709386-90747472 (-)
CBA/J MGP_CBAJ_G0029394
 protein coding gene Chr5:98611728-98649820 (-)
DBA/2J MGP_DBA2J_G0029538
 protein coding gene Chr5:88137222-88174835 (-)
FVB/NJ MGP_FVBNJ_G0029497
 protein coding gene Chr5:86996982-87034691 (-)
LP/J MGP_LPJ_G0029626
 protein coding gene Chr5:92058643-92101208 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029526
 protein coding gene Chr5:103605359-103646652 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030189
 protein coding gene Chr5:90461991-90500377 (-)
PWK/PhJ MGP_PWKPhJ_G0028553
 protein coding gene Chr5:87196176-87234451 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028388
 protein coding gene Chr5:89864107-89902783 (-)
WSB/EiJ MGP_WSBEiJ_G0028913
 protein coding gene Chr5:90919656-90957588 (-)



Homology
more
  • Human Ortholog
    RASSF6, Ras association domain family member 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RASSF6, Ras association domain family member 6
  • Links
    NCBI Gene ID: 166824
    neXtProt AC: NX_Q6ZTQ3
    UniProt: Q6ZTQ3

  • Chr Location
    4q13.3; chr4:73571550-73620631 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    3
  • Radiation induced
    1
  • Spontaneous
    1
  • Genomic Mutations
    4 involving Rassf6
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    21 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    782
  • Tissues
    12
  • cDNA Data
    20
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029370 Ensembl Gene Model | MGI Sequence Detail 37582 C57BL/6J ±  kb
transcript ENSMUST00000202704 Ensembl | MGI Sequence Detail 1178 Not Applicable  
polypeptide ENSMUSP00000144532 Ensembl | MGI Sequence Detail 341 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:330726 Morishita M, et al., Characterization of mouse embryonic fibroblasts derived from Rassf6 knockout mice shows the implication of Rassf6 in the regulation of NF-kappaB signaling. Genes Cells. 2021;26(12):999-1013
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory