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Fundc2b Gene Detail
Summary
  • Symbol
    Fundc2b
  • Name
    FUN14 domain containing 2B
  • Synonyms
    1700034I23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920547
    NCBI Gene: 73297
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:40854631-40856936 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 19.58 cM, cytoband C
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    137 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920547
protein coding gene Chr3:40854631-40856978 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027183
protein coding gene Chr3:38879647-38884098 (-)
A/J MGP_AJ_G0027143
protein coding gene Chr3:37936322-37941472 (-)
AKR/J MGP_AKRJ_G0027112
protein coding gene Chr3:38660573-38668264 (-)
BALB/cJ MGP_BALBcJ_G0027154
protein coding gene Chr3:37654841-37657004 (-)
C3H/HeJ MGP_C3HHeJ_G0026898
protein coding gene Chr3:38743666-38746080 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027601
protein coding gene Chr3:40447245-40449615 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0026350
protein coding gene Chr3:38577885-38580168 (+)
CBA/J MGP_CBAJ_G0026875
protein coding gene Chr3:41641210-41646768 (-)
DBA/2J MGP_DBA2J_G0027009
protein coding gene Chr3:37401324-37404408 (-)
FVB/NJ MGP_FVBNJ_G0026977
protein coding gene Chr3:36775393-36777977 (-)
LP/J MGP_LPJ_G0027121
protein coding gene Chr3:39622584-39624879 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0027660
protein coding gene Chr3:38477260-38482073 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0025896
protein coding gene Chr3:37908885-37911365 (-)
WSB/EiJ MGP_WSBEiJ_G0026425
protein coding gene Chr3:38523941-38525884 (-)



Homology
more
  • Human Ortholog
    FUNDC2, FUN14 domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FUNDC2, FUN14 domain containing 2
  • Synonyms
    DC44, HCBP6, HCC3, PD03104
  • Links
    NCBI Gene ID: 65991
    neXtProt AC: NX_Q9BWH2
    UniProt: Q9BWH2

  • Chr Location
    Xq28; chrX:155025980-155060304 (+)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 73297 NCBI Gene Model | MGI Sequence Detail 2306 C57BL/6J ±  kb
transcript NM_028494 RefSeq | MGI Sequence Detail 2306 C57BL/6  
polypeptide NP_082770 RefSeq | MGI Sequence Detail 184 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 4
Other
Accession IDs
less
MGI:7280771
References
more
  • Summaries
    All 28
    Diseases 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory