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Prss44 Gene Detail
Summary
  • Symbol
    Prss44
  • Name
    serine protease 44
  • Synonyms
    1700036D21Rik, TESSP4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920586
    NCBI Gene: 73336
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:110642987-110647067 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 60.79 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    202 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920586
 protein coding gene Chr9:110642987-110653591 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035357
 protein coding gene Chr9:113000418-113010933 (+)
A/J MGP_AJ_G0035338
 protein coding gene Chr9:108877718-108888252 (+)
AKR/J MGP_AKRJ_G0035269
 protein coding gene Chr9:111585324-111595815 (+)
BALB/cJ MGP_BALBcJ_G0035333
 protein coding gene Chr9:108625963-108640589 (+)
C3H/HeJ MGP_C3HHeJ_G0035041
 protein coding gene Chr9:112092968-112104483 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035855
 protein coding gene Chr9:116092726-116103278 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032741
 protein coding gene Chr9:106095691-106106631 (+)
CAST/EiJ MGP_CASTEiJ_G0034347
 protein coding gene Chr9:111886603-111897367 (+)
CBA/J MGP_CBAJ_G0035008
 protein coding gene Chr9:120388085-120402080 (+)
DBA/2J MGP_DBA2J_G0035167
 protein coding gene Chr9:108340207-108351017 (+)
FVB/NJ MGP_FVBNJ_G0035114
 protein coding gene Chr9:107171202-107183504 (+)
LP/J MGP_LPJ_G0035246
 protein coding gene Chr9:113289445-113300090 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035154
 protein coding gene Chr9:121713270-121724583 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035875
 protein coding gene Chr9:111931137-111941859 (+)
PWK/PhJ MGP_PWKPhJ_G0034054
 protein coding gene Chr9:108588402-108599750 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033889
 protein coding gene Chr9:112012488-112022851 (+)
WSB/EiJ MGP_WSBEiJ_G0034468
 protein coding gene Chr9:111794912-111806789 (+)



Homology
more
  • Human Ortholog
    PRSS44P, serine protease 44, pseudogene
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRSS44P, serine protease 44, pseudogene
  • Synonyms
    PRSS44, TESSP-4, TESSP4
  • Links
    NCBI Gene ID: 729756

  • Chr Location
    3p21.31; chr3:46808640-46812574 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Male mice homozygous for a null allele exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 73336 NCBI Gene Model | MGI Sequence Detail 4081 C57BL/6J ±  kb
transcript NM_148940 RefSeq | MGI Sequence Detail 1854 C57BL/6  
polypeptide Q402U7 UniProt | EBI | MGI Sequence Detail 372 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 7
Other
Accession IDs
less
MGI:2143237, MGI:2143238
References
more
  • Summaries
    All 27
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:279100 Holcomb RJ, et al., The testis-specific serine proteases Prss44, Prss46, and Prss54 are dispensable for mouse fertility. Biol Reprod. 2019 Aug 12;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory