Col20a1 MGI Mouse Gene Detail - MGI:1920618 - collagen, type XX, alpha 1

Symbol

Col20a1
Name

collagen, type XX, alpha 1
Synonyms

1700051I12Rik

Feature Type

protein coding gene
IDs

MGI:1920618
NCBI Gene: 73368
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr2:180628328-180660156 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 2, 103.53 cM
Mapping Data

1 experiment

SNPs within 2kb

766 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1920618	protein coding gene	Chr2:180626629-180660156 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0027008	protein coding gene	Chr2:187554811-187587566 (+)
A/J	MGP_AJ_G0026974	protein coding gene	Chr2:179839546-179871173 (+)
AKR/J	MGP_AKRJ_G0026944	protein coding gene	Chr2:185230061-185262367 (+)
BALB/cJ	MGP_BALBcJ_G0026983	protein coding gene	Chr2:180301311-180332234 (+)
C3H/HeJ	MGP_C3HHeJ_G0026724	protein coding gene	Chr2:185589009-185619930 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0027429	protein coding gene	Chr2:192980631-193011622 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0024794	protein coding gene	Chr2:170525734-170556188 (+)
CAST/EiJ	MGP_CASTEiJ_G0026183	protein coding gene	Chr2:183837401-183868459 (+)
CBA/J	MGP_CBAJ_G0026701	protein coding gene	Chr2:199974065-200008463 (+)
DBA/2J	MGP_DBA2J_G0026839	protein coding gene	Chr2:178932621-178963485 (+)
FVB/NJ	MGP_FVBNJ_G0026805	protein coding gene	Chr2:177546273-177580399 (+)
LP/J	MGP_LPJ_G0026940	protein coding gene	Chr2:187569736-187601863 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0026824	protein coding gene	Chr2:202548973-202580826 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0027488	protein coding gene	Chr2:185203385-185237227 (+)
PWK/PhJ	MGP_PWKPhJ_G0025919	protein coding gene	Chr2:176458119-176491914 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0025719	protein coding gene	Chr2:181688305-181719148 (+)
WSB/EiJ	MGP_WSBEiJ_G0026255	protein coding gene	Chr2:186188520-186223260 (+)

Human Ortholog

COL20A1, collagen type XX alpha 1 chain

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

COL20A1, collagen type XX alpha 1 chain
Links

HGNC:14670

NCBI Gene ID: 57642

neXtProt AC: NX_Q9P218

UniProt: Q9P218
Chr Location

20q13.33; chr20:63293186-63334851 (+) GRCh38

MGI Vertebrate Homology

Col20a1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: COL20A1
Gene Tree

Col20a1

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References

1 with disease annotations

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
10 phenotype references

All Mutations and Alleles

6
Endonuclease-mediated

3
Spontaneous

1
Targeted

2
Genomic Mutations

1 involving Col20a1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

48 strains or lines available

Male mice homozygous for a mutation are viable and show normal fertility.

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All GO Annotations

3
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

837
Tissues

42
cDNA Data

5
Literature Summary

3

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

47
RefSeq

9
UniProt

5
CCDS

CCDS50844.1

Ensembl

ENSMUSG00000016356 (Evidence)
NCBI Gene

73368

			Length	Strain/Species	Flank
genomic	ENSMUSG00000016356	Ensembl Gene Model \| MGI Sequence Detail	31829	C57BL/6J	± kb
transcript	ENSMUST00000108856	Ensembl \| MGI Sequence Detail	4489	Not Applicable
polypeptide	ENSMUSP00000104484	Ensembl \| MGI Sequence Detail	1362	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000005704 collagen alpha-1(XX) chain

(term hierarchy)
InterPro Domains

IPR050938 Collagen and Collagen-like Structural Proteins

IPR008160 Collagen triple helix repeat

IPR013320 Concanavalin A-like lectin/glucanase domain superfamily

IPR050525 Extracellular Matrix Assembly and Organization

IPR003961 Fibronectin type III

IPR036116 Fibronectin type III superfamily

IPR013783 Immunoglobulin-like fold

IPR048287 Thrombospondin-like, N-terminal domain

IPR036465 von Willebrand factor A-like domain superfamily

IPR002035 von Willebrand factor, type A
GlyGen

Q923P0 4 sites

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All nucleic 5

cDNA 5

Microarray probesets 2

Summaries

All 30

Developmental Gene Expression 3

Diseases 1

Gene Ontology 3

Phenotypes 10
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Col20a1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr22285	Chr2:180655227-180655238 (+)	26,905 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24