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Spmip8 Gene Detail
Summary
  • Symbol
    Spmip8
  • Name
    sperm microtubule inner protein 8
  • Synonyms
    1700055M20Rik, Tepp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920657
    NCBI Gene: 73407
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:96038148-96053239 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 47.12 cM, cytoband C5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    454 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920657
 protein coding gene Chr8:96037194-96053239 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033982
 protein coding gene Chr8:96791005-96808092 (+)
A/J MGP_AJ_G0033965
 protein coding gene Chr8:93003847-93019635 (+)
AKR/J MGP_AKRJ_G0033891
 protein coding gene Chr8:95528972-95544759 (+)
BALB/cJ MGP_BALBcJ_G0033957
 protein coding gene Chr8:93081732-93097505 (+)
C3H/HeJ MGP_C3HHeJ_G0033667
 protein coding gene Chr8:96262220-96278009 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034478
 protein coding gene Chr8:100318642-100334399 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031419
 protein coding gene Chr8:86800758-86817277 (+)
CAST/EiJ MGP_CASTEiJ_G0032999
 protein coding gene Chr8:95851950-95867767 (+)
CBA/J MGP_CBAJ_G0033643
 protein coding gene Chr8:103608867-103624677 (+)
DBA/2J MGP_DBA2J_G0033797
 protein coding gene Chr8:92487917-92503697 (+)
FVB/NJ MGP_FVBNJ_G0033744
 protein coding gene Chr8:91436182-91451989 (+)
LP/J MGP_LPJ_G0033889
 protein coding gene Chr8:96920608-96939197 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033786
 protein coding gene Chr8:105864466-105880223 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034496
 protein coding gene Chr8:95707281-95723115 (+)
PWK/PhJ MGP_PWKPhJ_G0032701
 protein coding gene Chr8:91849397-91865211 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032538
 protein coding gene Chr8:94564405-94580906 (+)
WSB/EiJ MGP_WSBEiJ_G0033111
 protein coding gene Chr8:96233001-96248757 (+)



Homology
more
  • Human Ortholog
    SPMIP8, sperm microtubule inner protein 8
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPMIP8, sperm microtubule inner protein 8
  • Synonyms
    TEPP
  • Links
    NCBI Gene ID: 374739
    neXtProt AC: NX_Q6URK8
    UniProt: Q6URK8

  • Chr Location
    16q21; chr16:57976435-57988116 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 73407 NCBI Gene Model | MGI Sequence Detail 15092 C57BL/6J ±  kb
transcript NM_199455 RefSeq | MGI Sequence Detail 898 C57BL/6  
polypeptide Q6IMH0 UniProt | EBI | MGI Sequence Detail 216 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 3
Other
Accession IDs
less
MGI:7470729
References
more
  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:338030 Zhou L, et al., Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility. Cell. 2023 Jun 22;186(13):2897-2910.e19
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory