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Apol7c Gene Detail
Summary
  • Symbol
    Apol7c
  • Name
    apolipoprotein L 7c
  • Synonyms
    2210421G13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920912
    NCBI Gene: 108956
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:77409052-77417516 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 36.40 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    388 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920912
 protein coding gene Chr15:77409052-77417540 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022022
 protein coding gene Chr15:77554704-77564026 (-)
A/J MGP_AJ_G0021987
 protein coding gene Chr15:74814392-74825744 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0021991
 protein coding gene Chr15:74924560-74932727 (-)
C3H/HeJ MGP_C3HHeJ_G0021765
 protein coding gene Chr15:77157774-77164950 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022435
 protein coding gene Chr15:80767367-80778446 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019963
 protein coding gene Chr15:71567107-71573423 (+)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0021854
 protein coding gene Chr15:74373120-74378262 (-)
FVB/NJ MGP_FVBNJ_G0021834
 protein coding gene Chr15:73281260-73318711 (-)
LP/J MGP_LPJ_G0021928
 protein coding gene Chr15:77872157-77878355 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021860
 protein coding gene Chr15:88521561-88527215 (+)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0021022
 protein coding gene Chr15:74390996-74396170 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0021333
 protein coding gene Chr15:77088395-77096589 (-)



Homology
more
  • Human Ortholog
    APOL2, apolipoprotein L2
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    APOL2, apolipoprotein L2
  • Synonyms
    APOL3, APOL-II
  • Links
    NCBI Gene ID: 23780
    neXtProt AC: NX_Q9BQE5
    UniProt: Q9BQE5

  • Chr Location
    22q12.3; chr22:36226209-36239954 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human APOL2,APOL4 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    2
  • Radiation induced
    2
  • Genomic Mutations
    4 involving Apol7c
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    22 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    25
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044309 Ensembl Gene Model | MGI Sequence Detail 8465 C57BL/6J ±  kb
transcript ENSMUST00000062562 Ensembl | MGI Sequence Detail 2060 Not Applicable  
polypeptide ENSMUSP00000050745 Ensembl | MGI Sequence Detail 369 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR008405 Apolipoprotein L
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 3
References
more
  • Summaries
    All 37
    Diseases 1
    Gene Ontology 1
    Phenotypes 21
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory