Tex19.1 MGI Mouse Gene Detail - MGI:1920929 - testis expressed gene 19.1

Symbol

Tex19.1
Name

testis expressed gene 19.1
Synonyms

2410081M02Rik, Tex19, Tex19.1

Feature Type

protein coding gene
IDs

MGI:1920929
NCBI Gene: 73679
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr11:121036969-121039140 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 85.00 cM
Mapping Data

4 experiments

SNPs within 2kb

137 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1920929	protein coding gene	Chr11:121036969-121039145 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0019539	protein coding gene	Chr11:125680200-125682376 (+)
A/J	MGP_AJ_G0019506	protein coding gene	Chr11:120069389-120071565 (+)
AKR/J	MGP_AKRJ_G0019476	protein coding gene	Chr11:123705451-123707627 (+)
BALB/cJ	MGP_BALBcJ_G0019481	protein coding gene	Chr11:120435949-120438125 (+)
C3H/HeJ	MGP_C3HHeJ_G0019287	protein coding gene	Chr11:124028915-124031091 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0019930	protein coding gene	Chr11:129494560-129496736 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017555	protein coding gene	Chr11:117047566-117049739 (+)
CAST/EiJ	MGP_CASTEiJ_G0018841	protein coding gene	Chr11:125529898-125532071 (+)
CBA/J	MGP_CBAJ_G0019258	protein coding gene	Chr11:134528933-134531109 (+)
DBA/2J	MGP_DBA2J_G0019371	protein coding gene	Chr11:119435073-119437249 (+)
FVB/NJ	MGP_FVBNJ_G0019362	protein coding gene	Chr11:119151784-119153959 (+)
LP/J	MGP_LPJ_G0019442	protein coding gene	Chr11:125959556-125961732 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019395	protein coding gene	Chr11:133342003-133344179 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019969	protein coding gene	Chr11:124380481-124382657 (+)
PWK/PhJ	MGP_PWKPhJ_G0018608	protein coding gene	Chr11:120879651-120881831 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0018399	protein coding gene	Chr11:124137052-124139228 (+)
WSB/EiJ	MGP_WSBEiJ_G0018894	protein coding gene	Chr11:124356984-124359160 (+)

Human Ortholog

TEX19, testis expressed 19

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TEX19, testis expressed 19
Links

HGNC:33802

NCBI Gene ID: 400629

neXtProt AC: NX_Q8NA77

UniProt: Q8NA77
Chr Location

17q25.3; chr17:82359247-82363775 (+) GRCh38

MGI Vertebrate Homology

Tex19.1 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: TEX19
Gene Tree

Tex19.1

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Phenotype Summary

32 phenotypes from 3 alleles in 3 genetic backgrounds
10 phenotypes from multigenic genotypes
15 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

14
Endonuclease-mediated

2
Gene trapped

1
Targeted

11
Incidental Mutations

APF , CvDC
Find Mice (IMSR)

10 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Mice homozygous for a knock-out allele exhibit decreased fertility, which in males is due to impaired spermatogenesis and increased male germ cell apoptosis.

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All GO Annotations

30
GO References

10

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

928
Tissues

73
cDNA Data

19
Literature Summary

10

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

34
RefSeq

2
UniProt

2
CCDS

CCDS25768.1

Ensembl

ENSMUSG00000039329 (Evidence)
NCBI Gene

73679

			Length	Strain/Species	Flank
genomic	73679	NCBI Gene Model \| MGI Sequence Detail	2172	C57BL/6J	± kb
transcript	NM_028602	RefSeq \| MGI Sequence Detail	1740	C57BL/6
polypeptide	Q99MV2	UniProt \| EBI \| MGI Sequence Detail	351	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000016923 testis-expressed protein 19A

(term hierarchy)
InterPro Domains

IPR029093 Testis-expressed protein 19

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All nucleic 26

cDNA 19

Primer pair 5

Other 2

Microarray probesets 2

Summaries

All 43

Developmental Gene Expression 10

Gene Ontology 10

Phenotypes 15
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:291759 Reichmann J, et al., Tex19.1 inhibits the N-end rule pathway and maintains acetylated SMC3 cohesin and sister chromatid cohesion in oocytes. J Cell Biol. 2020 May 4;219(5)

TSS for Tex19.1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr106391	Chr11:121036972-121036986 (+)	10 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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