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Lce1a2 Gene Detail
Summary
  • Symbol
    Lce1a2
  • Name
    late cornified envelope 1A2
  • Synonyms
    1110004E04Rik, Sprrl2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920972
    NCBI Gene: 73722
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:92575920-92577622 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 40.14 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    172 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920972
 protein coding gene Chr3:92575920-92577622 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027508
 protein coding gene Chr3:93126746-93128448 (-)
A/J MGP_AJ_G0027475
 protein coding gene Chr3:90196306-90198123 (-)
AKR/J MGP_AKRJ_G0027440
 protein coding gene Chr3:92311192-92312894 (-)
BALB/cJ MGP_BALBcJ_G0027483
 protein coding gene Chr3:90007812-90009519 (-)
C3H/HeJ MGP_C3HHeJ_G0027223
 protein coding gene Chr3:92533237-92534939 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027927
 protein coding gene Chr3:96670283-96671985 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025274
 protein coding gene Chr3:86802096-86802810 (-)
CAST/EiJ MGP_CASTEiJ_G0026668
 protein coding gene Chr3:91918863-91925086 (-)
CBA/J MGP_CBAJ_G0027197
 protein coding gene Chr3:99992811-99994513 (-)
DBA/2J MGP_DBA2J_G0027335
 protein coding gene Chr3:89517070-89518772 (-)
FVB/NJ MGP_FVBNJ_G0027303
 protein coding gene Chr3:87685143-87686845 (-)
LP/J MGP_LPJ_G0027443
 protein coding gene Chr3:94345484-94347186 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027328
 protein coding gene Chr3:106275712-106277418 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027986
 protein coding gene Chr3:92039974-92041676 (-)
PWK/PhJ MGP_PWKPhJ_G0026401
 protein coding gene Chr3:89374946-89375676 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0026753
 protein coding gene Chr3:92425305-92427011 (-)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Lce1a2
  • Find Mice (IMSR)
    6 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • cDNA Data
    10
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 73722 NCBI Gene Model | MGI Sequence Detail 1703 C57BL/6J ±  kb
transcript NM_028625 RefSeq | MGI Sequence Detail 715 C57BL/6  
polypeptide NP_082901 RefSeq | MGI Sequence Detail 149 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR028205 Late cornified envelope protein
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Developmental Gene Expression 6
    Diseases 1
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory