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Klk9 Gene Detail
Summary
  • Symbol
    Klk9
  • Name
    kallikrein related-peptidase 9
  • Synonyms
    1200016C12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921082
    NCBI Gene: 101533
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:43441315-43446181 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 28.26 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    169 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921082
protein coding gene Chr7:43441048-43446182 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032142
protein coding gene Chr7:43833515-43840533 (+)
A/J MGP_AJ_G0032127
protein coding gene Chr7:42921835-42926718 (+)
AKR/J MGP_AKRJ_G0032057
protein coding gene Chr7:44305935-44310800 (+)
BALB/cJ MGP_BALBcJ_G0032132
protein coding gene Chr7:43038382-43043223 (+)
C3H/HeJ MGP_C3HHeJ_G0031848
protein coding gene Chr7:44813904-44818808 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032616
protein coding gene Chr7:46041540-46048552 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029639
protein coding gene Chr7:45055970-45060933 (+)
CAST/EiJ MGP_CASTEiJ_G0031178
protein coding gene Chr7:36001695-36007597 (+)
CBA/J MGP_CBAJ_G0031817
protein coding gene Chr7:47504557-47512345 (+)
DBA/2J MGP_DBA2J_G0031966
protein coding gene Chr7:42728615-42733529 (+)
FVB/NJ MGP_FVBNJ_G0031927
protein coding gene Chr7:42439680-42444509 (+)
LP/J MGP_LPJ_G0032045
protein coding gene Chr7:44561131-44566023 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031963
protein coding gene Chr7:46428922-46435187 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032636
protein coding gene Chr7:43432872-43437749 (+)
PWK/PhJ MGP_PWKPhJ_G0030899
protein coding gene Chr7:36178752-36184020 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030738
protein coding gene Chr7:31463149-31467945 (+)
WSB/EiJ MGP_WSBEiJ_G0031292
protein coding gene Chr7:43981090-43986953 (+)



Homology
more
  • Human Ortholog
    KLK9, kallikrein related peptidase 9
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KLK9, kallikrein related peptidase 9
  • Synonyms
    KLK-L3, KLKL3
  • Links
    NCBI Gene ID: 284366
    neXtProt AC: NX_Q9UKQ9
    UniProt: Q9UKQ9

  • Chr Location
    19q13.41; chr19:51002508-51009634 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047884 Ensembl Gene Model | MGI Sequence Detail 4867 C57BL/6J ±  kb
transcript ENSMUST00000005891 Ensembl | MGI Sequence Detail 1476 Not Applicable  
polypeptide ENSMUSP00000005891 Ensembl | MGI Sequence Detail 251 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
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  • All nucleic 7
    cDNA 7

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141910
References
more
  • Summaries
    All 28
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory